Canon Kabushiki Kaisha

Canon Medical Systems Corporation

Takahiro Masumura

Shuichi Kobayashi

Shigeru Ichihara

Hirotoshi Tahara

Toshihiro Fukumoto

Satoru Sugita

A measuring apparatus is configured to acquire information on a target. The measuring apparatus includes an irradiating unit configured to irradiate a specific area of the target with irradiation light, a detecting unit configured to receive exit light from the target which is caused by irradiating the specific area with the irradiation light, and a processing unit configured to process a signal output from the detecting unit. The processing unit causes the irradiating unit to shape a wavefront of the irradiation light by feeding back a first signal output from the detecting unit that has received the exit light. The processing unit acquires information about the specific area using a second signal output from the detecting unit that has received exit light from the target which is by irradiating the specific area with irradiation light having a shaped wavefront.

Measuring apparatus, measuring method, and storage medium

An automatic analysis apparatus includes a reaction vessel configured to contain a reaction liquid in which a measuring object and a reagent are mixed with each other, an irradiation unit configured to irradiate the reaction vessel with irradiation light as predetermined incident light polarization, a measurement unit configured to measure light emitted from the reaction vessel, and a processor configured to process a signal having a specific polarization component obtained from the measurement unit and to analyze the measuring object. The specific polarization component is determined based on the condition of the reaction liquid.

Automatic analysis apparatus, automatic analysis method, and storage medium

A wavefront control apparatus includes a detector configured to detect a signal generated from a medium onto which light is irradiated, and a controller configured to control a wavefront of the light based on an output of the detector. The controller performs first processing for forming a first wavefront of the light based on the signal generated from a first measurement position in the medium, and second processing for forming a second wavefront of the light based on the signal generated from a second measurement position different from the first measurement position in the medium onto which the light having the first wavefront is irradiated.

Wavefront control apparatus, wavefront control method, information acquiring apparatus, and storage medium

An image capturing apparatus includes a spatial light modulator configured to shape a wavefront of light traveling from a light source to an object, an image capturer configured to generate image data by capturing an image of the object, and a controller configured to control the spatial light modulator and to make the image capturer capture the image when object light among the light reaches the image capturer via the object. The controller performs an optimization control of the spatial light modulator so as to maximum or minimize a value of an objective function set by using a luminance value in a target area corresponding to the object light in the image data.

Image capturing apparatus, image capturing method, and storage medium

A method for irradiating a medium includes irradiating the medium with an electromagnetic wave which is scattered in the medium and modulated in frequency at a position in the medium; obtaining information corresponding to an interference pattern generated by interference between the modulated electromagnetic wave and a reference wave; and generating a phase conjugate wave, based on the obtained information, which irradiates the medium.

Apparatus and method for irradiating a medium

A control apparatus includes a data acquiring unit configured to acquire a measured signal obtained by measuring light emitted from a test object onto which light is irradiated, a processing unit configured to calculate an objective function that varies in accordance with a statistical value obtained by statistically processing the measured signal, and a controller configured to control a modulation amount of a wavefront of the light irradiated onto the test object so as to minimize the objective function.

Control apparatus, measurement apparatus, control method, and storage medium

A method for irradiating a medium with a wave which is designed to focus on a particular portion in the medium, the method includes: irradiating the medium with an electromagnetic wave which is scattered in the medium, and is not designed to focus on the particular portion in the medium; detecting a first signal caused by irradiating the medium with the electromagnetic waver; irradiating the medium with a reconstructed wave which is designed to focus on the particular portion in the medium; detecting a second signal caused by irradiating the medium with the reconstructed wave; and monitoring, based on the first and second signals, that the particular portion is irradiated by the reconstructed wave.

A system and method for irradiating a medium including irradiating the medium with an electromagnetic wave which is scattered in the medium and modulated in frequency at a position in the medium; obtaining information corresponding to an interference pattern generated by interference between the modulated electromagnetic wave and a reference wave; and generating a phase conjugate wave, based on the obtained information, which irradiates the medium.

Apparatus and method for irradiating a scattering medium with a reconstructive wave

An apparatus includes a low-coherent light source configured to emit an electromagnetic wave; a spatial light modulator configured to modulate a wavefront of the electromagnetic wave; an interferometer including a movable mirror to set a depth of a medium to be irradiated by the electromagnetic wave and a beam splitter configured to the electromagnetic wave into a reference beam and an object beam; a detector to detect information about an interference pattern formed by the object beam coming from the medium via the beam splitter and the reference beam reflected by the movable mirror; and a controller configured to control the spatial light modulator, based on the information, to form a modulated wavefront for irradiating the medium.

Apparatus and method for irradiating a scattering medium

An apparatus includes a light source configured to emit an electromagnetic wave; a spatial light modulator configured to modulate a wavefront of the electromagnetic wave to irradiate a sample; a plate with an aperture; a lens unit configured to set a focal point in the sample; a detector configured to detect light coming from the focal point of the sample through the aperture; and a controller configured to control the spatial light modulator based on the detected light by the detector.

A biological information processing apparatus includes the following elements. A light source irradiates biological tissue with light. A transducer functions as an ultrasonic wave transmitting unit that applies an ultrasonic wave to a local region in the biological tissue. A photodetector detects modulated light obtained by modulating the light from the light source with the ultrasonic wave in the local region. The transducer also functions as an acoustic wave detecting unit that detects an acoustic wave emitted from the local region at a time when the local region absorbs the light from the light source. An absorption characteristic in the local region is calculated using an acoustic signal, serving as an output of the acoustic wave detecting unit, on the basis of a light intensity in the local region calculated based on a modulation signal, serving as an output of the photodetector.

Apparatus and method for processing biological information

Disclosed is a photoacoustic measurement apparatus that irradiates a light beam onto a subject, from a same side as that of an acoustic wave detector, and that measures photoacoustic waves. The photoacoustic measurement apparatus has: an acoustic wave detector; a diffraction grating member provided in front of a detection surface of the detector; a light source that generates a light beam; and an optical system that guides the light beam from the light source towards the diffraction grating member. The diffraction grating member is configured such that the light beam led to the diffraction grating member is outputted by the diffraction grating member towards a subject surface that opposes the detection surface of the detector. As a result, light beams can strike a biological body in a near-perpendicular angle. This affords greater illumination efficiency, and allows light of substantial light energy to be irradiated deep inside biological structures.

Photoacoustic measurement apparatus

A measurement apparatus includes an elastic detector configured to detect an elastic wave by utilizing photoacoustic tomography and to convert the elastic wave into a detection signal, and a signal processor configured to calculate an absorption characteristic of a heterogeneous part included in a homogeneous part of a scattering medium based on &#x3bc;=2P(z)/(&#x393;&#x3a6;(z)) where &#x3bc;is the absorption coefficient at distance z from the light source, P(z) is the pressure of the elastic wave at distance z, &#x393; is a Gr&#xfc;neisen coefficient, and &#x3a6;(z) is the light intensity at the position of the heterogeneous part, the signal processor obtaining the light intensity by approximating a signal component derived from the homogeneous part separated from a signal component derived from the heterogeneous part in the scattering medium by utilizing the detection signal output from the elastic wave detector.

Measurement apparatus

A measurement apparatus includes a measurement unit configured to irradiate three types of ultrasonic waves and light upon a test region in a test object, and to measure modulated light and non-modulated light, the modulated light being modulated by an acousto-optical effect, and a signal processor configured to calculate a modulation depth that is an intensity of the modulated light divided by an intensity of the non-modulated light for the one, and at least one of a scattering characteristic and an absorption characteristic of the test region in the test object by utilizing a first change rate of the modulation depth to an amplitude of the one or an amount corresponding to the first change rate, and a second change rate of the modulation depth to a frequency of the one or an amount corresponding to the second change rate.

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Utsunomiya, Japan

Takahiro Masumura