Sony Corporation

Astellas Pharma Gmbh

Icagen, Inc.

Mitsubishi Electric Corporation

Disco Corporation

Tokyo Institute of Technology

Meiji Seika Kaisha, Ltd.

Takahiro Ishii

Takashi Sugane

Yasushi Fukuda

Shiho Nagano

Kentaro Sato

Jun Maeda

Takatoshi Kanayama

Akio Kakefuda

Tatsuhisa Takahashi

Chikashi Saitoh

Jotaro Suzuki

Chisato Kanai

Fumie Narazaki

Takashi Totsuka

Takeshi Suzuki

Xiaodong Wang

Kerry Leigh Spear

Alan Bradley Fulp

Darrick Seconi

Naosuke Asari

Ayako Moritomo

Seiji Kobayashi

Satoshi Aoki

Taro Niida

Youngsuk Kim

Noriyuki Kawano

Byeongdeck Jang

Daisuke Matsuura

Takeshi Matsumoto

Yujiro Yamada

Hidetoshi Nagano

Eiichi Akita

Daisuke Nakazawa

Masayuki Kakio

Takeo Miyazawa

Ryosuke Munakata

Kiyohiro Samizu

Yuzo Kazuno

Daichi Sasaki

Yukio Takeda

Tomotaka Ogino

Yusuke Sugahara

Maki Sakai

Hiromasa Oka

Xiadong Wang

There is provided a conveying device that can support a car weight with a mechanism lighter in weight. A driving device () of a conveying device that lifts and lowers a loading-weight support along a rail () includes a wheel unit () and a link (). The wheel unit () drives to rotate a driving wheel () in contact with a guide surface () to lift and lower the loading-weight support. The link () includes a first joint () connected to the wheel unit () and a second joint () rotatably supported by the loading-weight support. The second joint () is arranged in a position further apart from the guide surface () than the first joint (), and above the first joint (). The link () is arranged such that a straight line connecting the first joint () and the second joint () is tilted smaller than 45 degrees.

Conveying device

A multi blade that processes semiconductor packages into a desired shape while dividing a package substrate includes plural cutting blades that divide the package substrate into the individual semiconductor packages and a spacer provided between two cutting blades adjacent to each other, and is configured in such a manner that the cutting blades and the spacer have the same rotation axis center. The outer surface of the spacer is formed into a transfer shape of the semiconductor package and is covered by an abrasive grain layer, and the upper surface of the package substrate is ground by the outer surface of the spacer simultaneously with cutting of the package substrate by the plural cutting blades.

Multi-blade and processing method of workpiece

A compound which is useful as an active ingredient of a pharmaceutical composition for treating neuropathic pain is provided. The present inventors have made extensive studies on compounds having an FAAH inhibitory activity, and as a result, have found that an azole compound substituted with an N-(pyridine-3-yl)oxycarbonyl-piperidin-4-yl group and a phenyl group or a pharmaceutically acceptable salt thereof has an excellent FAAH inhibitory activity, thereby completing the present invention. The compound of the present invention is confirmed to have an excellent FAAH inhibitory activity and an antiallodynic effect in rat models with neuropathic pain, and thus is useful as an agent for preventing and/or an agent for treating neuropathic pain.

Azole compound

A restored image is reconstructed from a thinned image to which no motion vector is incident. There is provided a moving picture converting apparatus for restoring a string of thinned images resulted from thinning pixels of an original-image string, which includes an input unit to receive the thinned-image string, an initial motion vector detector to detect a string of motion vector images on the basis of the thinned-image string, a reconstructing unit to reconstruct, each time a new motion vector image string is detected, a string of restored images on the basis of the new restored-image string and previous detected-motion vector image strings, a motion vector detector to detect, each time a new string of restored images is reconstructed, a new string of motion vector images based on the new restored-image string and previous detected-motion vector image strings, and a process terminating unit to terminate the reconstructing process by the reconstructing unit and motion vector detecting process by the motion vector detector and output a restored image, which has been restored, of the restored-image string obtained at the time of deciding the process termination.

Moving picture converting apparatus and method, and computer program

A novel pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate compound and its pharmaceutically acceptable salt has a potent FAAH-inhibitory activity. Further, the pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate compound of the present disclosure is also useful in the treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain.

Pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate compound

To provide a compound usable for treatment of diseases associated with fatty acid amide hydrolase (FAAH), especially for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain. We have found that a novel pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative and its pharmaceutically acceptable salt has a potent FAAH-inhibitory activity. Further, the pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate derivative of the present invention has an excellent effect for increasing an effective bladder capacity, an excellent effect for relieving urinary frequency and an excellent anti-allodynia effect, and is therefore usable for treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain.

A novel pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate compound or its pharmaceutically acceptable salt has a potent FAAH-inhibitory activity. Further, the pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate compound of the present disclosure is also useful in the treatment of urinary frequency and urinary incontinence, overactive bladder and/or pain.

The present invention provides a genus of polycyclic pyrazines of formula (I): wherein A and B are independently substituted or unsubstituted 5- or 6- membered heterocycloalkyl, or substituted or unsubstituted 5- or 6- membered heteroaryl, Wis Wis &#x2014;CH&#x2550;, &#x2014;NH&#x2014;, &#x2014;N&#x2550;, &#x2014;S&#x2014;, or &#x2014;O&#x2014;; Zis Zis &#x2014;CH&#x2550;, &#x2014;NH&#x2014;, &#x2014;N&#x2550;, &#x2014;S&#x2014;, or &#x2014;O&#x2014;; Y is a bond, &#x2014;CH&#x2550;N&#x2014;NH&#x2014;, &#x2014;NH&#x2014;CH, or &#x2014;NR&#x2014;; s and t are independently integers from 1 to 4; and the substituents R, R, Rand Rare as defined in the specification for compounds of formula (I). The polycyclic pyrazine compounds are useful as modulators of potassium ion channels in both therapeutic and diagnostic methods.

Polycyclic pyrazines as potassium ion channel modulators

It is intended to restore moving-picture data whose pixels have been thinned rapidly with a small-capacity memory and with prevention of image deterioration. There is provided a moving picture converting apparatus for reconstructing an original moving picture from compressed moving-picture data, which includes an input unit to receive compressed moving-picture data including a thinned image consisting of invalid pixels and valid pixels and a forward motion vector incident to the thinned image, an intra-frame interpolator for interpolating the invalid pixels in a present frame to be restored on the basis of the valid pixels of the thinned image in the present frame to produce a padded image, and a frame rendering unit to produce a rendered image by making preceding-frame rendering to restore pixels of the padded image on the basis of valid pixels in a preceding frame and subsequent-frame rendering to restore pixels of the padded image on the basis of valid pixels in a subsequent frame, the frame rendering unit making the preceding-frame rendering to restore a pixel at an end point of tracing in the padded image on the basis of valid pixels detected in the process of tracing, started at a pixel in the preceding frame, in a sequence from the preceding frame to the present frame according to the forward motion vector, and the subsequent-frame rendering to restore a pixel at the start point of the tracing in the padded image on the basis of valid pixels detected in the process of tracing, started at an invalid pixel of the padded image in the present frame, in a sequence from the present frame to the subsequent frame according to the forward motion vector.

The present invention provides a genus of polycyclic pyrimidines that are useful as modulators of potassium ion channels. The modulators of the invention are of use in both therapeutic and diagnostic methods.

Polycyclic pyrimidines as potassium ion channel modulators

An image processing apparatus and method produce sectional image data of a specimen in an arbitrary direction without deterioration of picture quality. A re-construction process produces volume data such that one of coordinate axes of a volume coordinate system such as the z axis is aligned with the principal axis of inertia of a specimen. When sectional image data of the specimen on a certain section are to be produced, from among all voxels which compose the volume data, those voxels whose z coordinates have predetermined values are read out, and the read out voxels are regarded as pixels. As a result, it is not necessary to interpolate pixels, and the deterioration of picture quality arising from interpolation of pixels is prevented.

Image processing apparatus and method, program, and image processing system

An image information processing apparatus generating three-dimensional volume data corresponding to a sample on the basis of two-dimensional projection data of the sample from a full circumferential direction acquired by an image capturing apparatus comprising an irradiation unit irradiating transmittable energy onto the sample; a photo detector receiving the energy through the sample; and a rotator rotating the sample is provided. The apparatus includes correcting means correcting pixels of said projection image data depending on an inclination angle of the rotator determined on the basis of a rotation axis of the rotator and an irradiation axis of the irradiation unit; filtering means giving a prescribed filtering processing to projection image data pixels having been corrected by the correcting means; and voxel calculating means calculating voxels of the volume data using the projection image data pixels having been given the filtering processing and depending on the inclination angle of the rotator.

Image information processing apparatus, image information processing method, and program

An image processing apparatus, for equally dividing an area of an arbitrary figure by pixel units by a number of parallel lines, which includes an input element for inputting a dividing number for a figure obtaining element which obtains a total number of pixels of the figure, a calculating element for calculating an initial ideal value by dividing the total number of pixels by the dividing number, a computing element for computing an ideal value of the number of pixels of a kth divided region in the figure using the initial ideal value and a sum of determined values of the numbers of pixels of a first to a (k&#x2212;1)th divided region, and a determining element for determining a determined value of the number of pixels of the kth divided region such that an error between the determined value of the number of pixels of the kth divided region and the ideal value of the number of pixels of the kth divided region is minimized.

Image processing apparatus and method, recording medium, and program

Growing community of inventors

Tokyo, Japan

Takahiro Ishii