Nippon Kayaku Kabushiki Kaisha

Takara Shuzo Co., Inc.

Takaru Shuzo Co., Ltd.

Takaaki Ohkuma

Yoshihisa Umeda

Hironobu Hiraga

Ikunoshin Kato

Katsushige Ikai

Tetsushi Saino

Hiroshi Ninomiya

Makoto Moriguchi

Masaaki Nakamura

Emiko Yamasaki

Genichi Idzu

The invention provides crystalline deoxyspergualin trihydrochloride, a process for the preparation of the same and a suppository composition containing the same. The compound and composition has antitumor and immunosuppressing activity.

Crystalline deoxyspergualin, process for its preparation and suppository

The invention provides crystalline deoxyspergualin trihydrochloride, a process for the preparation of the same and a suppository composition containing the same. The compound and composition has antitumor and immunosuppressive activity.

A lyophilized preparation comprising 6-(3-dimethylaminopropionyl)forskolin, a buffer agent having a pH value of about 3 to about 6 when dissolved, and, as an optional ingredient, a sugar. The lyophilized preparation is excellent in resolubility and stable in both pH and residual percentage.

Lyophilized preparation of 6-(3-dimethylaminopropionyl)forskolin

An aqueous solution of nitroglycerin comprising at least one substance selected from among sorbitol, mannitol and xylitol in addition to nitroglycerin, and having a high degree of stability for storage.

Aqueous solution of nitroglycerin

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Yono, Japan

Takaaki Ohkuma