Mitsubishi Electric Corporation

Mitsubishi Denki Kabushiki Kaisha

Mitsubishi Electric Company

Hitachi, Ltd.

Takaaki Iwata

Hisashi Harada

Yuehu Pu

Taizo Honda

Yuichi Yamamoto

Masahiro Ikeda

Yoshihito Imai

Toshihiro Otani

Hidenobu Sakamoto

Teiji Takahashi

Hiroyoshi Omura

Takeshi Sakata

Osamu Takahashi

Tatsushi Sato

Shigeru Matsuno

Shuhei Nakata

Kazushi Hanakawa

Yoichiro Nishimoto

Kengo Sugahara

Katsuhisa Yoshida

Tomoko Sendai

Takeyuki Maegawa

Tetsuya Shiroishi

Nobuhiko Ina

Yukiko Yamada

Akihiko Hosono

Tetsuya Ootsuki

Toshiyuki Hokodate

Kazuyuki Tsuchiya

Yuehu Fu

In particle beam irradiation equipment, a control unit causes a storage unit to store, as position information of reference positions, position information of electromagnets that is acquired at the time of their first alignment, by cameras, and then acquires displacement amounts, based on the position information of the reference positions stored in the storage unit and from position information of the electromagnets acquired at the time of their realignment, by the cameras.

Particle beam irradiation equipment

A scanning candidate route extracting unit which extracts plural candidates of scanning routes in which each of the scanning routes connects all spot positions in one layer is provided, in an evaluation function using necessary scanning time Tk and weight coefficient wk for a kth partial route among partial routes which are routes between the spot positions which are adjacent on one of the plural candidates of scanning routes, and number n of spot in the layer, wk with respect to a partial route which passes through affected tissue is set to be 1, wk with respect to a partial route which passes through normal tissue is set to be bigger than 1, and wk with respect to a partial route which passes through an important internal organ is set to be bigger than wk with respect to a partial route which passes through normal tissue.

Treatment planning device, particle beam therapy system and method for determining scanning route of charged particle beam

An irradiation apparatus radiates a particle beam after forming the beam for plural layers. A dose monitor measures a dose in real time. A dose evaluation unit evaluates an irradiation dose for each layer on the basis of a value measured by the dose monitor and a dose calibration factor set for each layer. An irradiation control section performs radiation control for each layer on the basis of an evaluation result of the dose evaluation unit. An interpolation value generation unit uses actual-measurement dose-calibration factors obtained by radiating a particle beam to a simulated phantom provided with a calibration dosimeter, to generate an interpolation estimation value of the dose calibration factor. For each layer subject to the interpolation value, and based on an irradiation condition of that layer, the interpolation value generation unit performs weighting on each of the actual-measurement dose-calibration factors.

Particle therapy device and method for setting dose calibration factor

When IMRT technology for a radiation therapy system utilizing an X-ray or the like is applied to a particle beam therapy system having a conventional wobbler system, it is required to utilize two or more boluses. The present invention solves the problem of excess irradiation in IMRT by a particle beam therapy system. More specifically, the problem of excess irradiation in IMRT by a particle beam therapy system is solved by raising the irradiation flexibility in the depth direction, without utilizing a bolus. A particle beam irradiation apparatus has a scanning irradiation system that performs scanning with a charged particle beam accelerated by an accelerator and is mounted in a rotating gantry for rotating the irradiation direction of the charged particle beam. The particle beam irradiation apparatus comprises a columnar-irradiation-field generation apparatus that generates a columnar irradiation field by enlarging the Bragg peak of the charged particle beam.

Particle beam irradiation apparatus and particle beam therapy system

A control device (control unit) to be used for controlling a scanning electromagnet that is used for scanning irradiation, which includes: a command-value processing line (a memory, an arithmetic circuit, an interface) that generates a command value for driving the scanning electromagnet on the basis of a treatment plan, and outputs the generated command value in synchronization with an accelerator; and a comparator unit that detects an error in the processing line; wherein a circuit (for example, the arithmetic circuit) that constitutes at least a part of the processing line is made redundant, and the comparator unit detects occurrence of the error in the processing line when outputs from the circuit made redundant are unmatched to each other.

Control device for scanning electromagnet and particle beam therapy apapratus

In the particle beam therapy system, a beam transport system includes a beam-path changer for changing a beam path so as to transport a charged particle beam to any one of the plurality of particle beam irradiation apparatuses; and a treatment management device includes a beam-path controller that generates an emitter control signal for controlling an emitter of an accelerator and a beam-path changer control signal for controlling the beam-path changer so that, with respect to the plurality of particle beam irradiation apparatuses in which treatment is performed at the same treatment period of time, the charged particle beam is transported to each one of the plurality of particle beam irradiation apparatuses for each time period allocated thereto.

Particle beam therapy system

A scanning candidate route extracting unit which extracts plural candidates of scanning routes in which each of the scanning routes connects all spot positions in one layer is provided, in an evaluation function using necessary scanning time Tk and weight coefficient wk for a kth partial route among partial routes which are routes between the spot positons which are adjacent on one of the plural candidates of scanning routes, and number n of spot in the layer, wk with respect to a partial route which passes through affected tissue is set to be 1, wk with respect to a partial route which passes through normal tissue is set to be bigger than 1, and wk with respect to a partial route which passes through an important internal organ is set to be bigger than wk with respect to a partial route which passes through normal tissue.

There are provided a leaf row in which a plurality of leaf plates are arranged in the thickness direction of the row in such a way that the respective one end faces of the leaf plates are trued up and a leaf plate drive mechanism that drives each of the plurality of leaf plates in such a way that the one end face approaches or departs from a beam axis. In each of the leaf plates, a facing side facing a leaf plate that is adjacent to that leaf plate in the thickness direction is formed of a plane including a first axis on the beam axis; the leaf plate drive mechanism drives the leaf plate along a circumferential orbit around the second axis, on the beam axis, that is perpendicular to the beam axis and the first axis.

Multi-leaf collimator, particle beam therapy system, and treatment planning apparatus

The particle beam irradiation apparatus comprises: a position monitor that detects a passing position of a charged particle beam; and an irradiation control apparatus that calculates a distance from a predetermined reference point to the position monitor, calculates a beam irradiation position on an irradiation subject, and controls irradiation of the beam; wherein the irradiation control apparatus includes a position calculation apparatus that calculates the beam irradiation position, based on a beam position detected by the position monitor, a scanning starting point distance information on a distance from a irradiation plane of the irradiation subject to a scanning starting point, of the beam, in a scanning electromagnet, and a position monitor distance information on a distance, from the irradiation plane to the position monitor, that is calculated based on the calculated distance.

Particle beam irradiation apparatus and particle beam therapy system utilizing a beam position monitor to provide feedback adjustments based on the beam position

A scanning power source that outputs the excitation current for a scanning electromagnet and an irradiation control apparatus that controls the scanning power source; the irradiation control apparatus is provided with a scanning electromagnet command value learning generator that evaluates the result of a run-through, which is a series of irradiation operations through a command value for the excitation current outputted from the scanning power source, that updates the command value for the excitation current, when the result of the evaluation does not satisfy a predetermined condition, so as to perform the run-through, and that outputs to the scanning power source the command value for the excitation current such that its evaluation result has satisfied the predetermined condition.

There is provided a particle-beam energy changing apparatus that is capable of changing energy of a particle beam quickly and silently, in which a first energy changing unit and a second energy changing unit for changing energy of a particle beam passing therethrough by varying thicknesses of their attenuators attenuating the particle beam energy are arranged so that the particle beam passes through the first energy changing unit and the second energy changing unit; and the maximum attenuation amount by the first energy changing unit is set smaller than the maximum attenuation amount by the second energy changing unit.

Particle-beam energy changing apparatus, particle beam therapy system including the same, and method of changing particle beam energy

The objective is to obtain a respiratory induction apparatus and a particle beam therapy system in which respiration can appropriately be induced by accurately evaluating the respiration. There are provided a respiratory induction control unit (C) that generates a desired respiratory signal (R(t)) for respiratory induction; a real respiration measurement unit () that outputs a real respiratory signal (R(t)) obtained by measuring real respiration of a patient; and a respiration evaluation unit (E) in which by, as a unit, utilizing data of a single period (T) of the desired respiratory signal (R(t)), there is calculated a pair of coefficients (aand b), of trigonometric functions, which correspond to the 1st-order terms by means of Fourier series expansion of data of the desired respiratory signal (R(t)) and data of the real respiratory signal (R(t)), which is acquired in synchronization with the data of the desired respiratory signal (R(t)), and there are performed comparisons between the respective gains (Gand G) and between the respective phases (&#x3c6;and &#x3c6;), which are obtained from the coefficients (aand b), so that there is evaluated a misalignment of the real respiration from the desired respiratory signal.

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Tokyo, Japan

Takaaki Iwata