Shimadzu Corporation

Phytronix Technologies Inc.

Tairo Ogura

Yuko Kobayashi

Yuka Fujito

Pierre Picard

Hiroshi Sugawara

Jean Lacoursiere

Kenichiro Tanaka

A mass spectrometry control device includes a deriver that derives, based on a set of allergens that are detectable without being distinguished from one another among a plurality of allergens to be detected and data that indicates a plurality of peptides produced by subjecting each allergen to a cleavage process, first peptides produced in common when the plurality of allergens included in the set are subjected to the cleavage process and at least one of parameters for detecting the first peptides, and a setter that sets a condition of mass spectrometry to detect at least one of the first peptides.

Mass spectrometry control device, mass spectrometry device, mass spectrometry method and a non-transitory computer readable medium storing program

An analysis device for data obtained in mass spectrometry, includes an information acquirer that acquires detection information representing a peptide that is detected when a sample is subjected to a cleavage process and then subjected to mass spectrometry, and an information producer that produces allergen information in regard to an allergen included in the sample based on the detection information and data representing a peptide that is produced when each allergen is subjected to the cleavage process, wherein the information producer produces the allergen information based on a combination of a plurality of peptides in a case in which the plurality of peptides produced from one allergen in the data are detected.

Analysis device for data obtained in mass spectrometry, mass spectrometry device, analysis method for data obtained in mass spectrometry and non-transitory computer readable medium storing analysis program

A supercritical fluid device includes an analytical channel, a liquid delivery part for delivering a mobile phase constituting a supercritical fluid in the analytical channel, a back pressure regulator for controlling a pressure of the analytical channel so as to cause the mobile phase in the analytical channel to reach a supercritical state, a sample injecting device that includes a sample holder for holding a sample and a switching valve for switching between a state where the sample holder is arranged on the analytical channel and a state where the sample holder is not arranged on the analytical channel, a bypass channel whose one end is connected to a position upstream of the sample injecting device and whose other end is connected to a position downstream of the sample injecting device on the analytical channel, and an analytical column for separating a sample introduced by the sample injecting device into individual components, the analytical column is provided downstream of the position to which the other end of the bypass channel is connected on the analytical channel.

Supercritical fluid device

A mass spectrometer having a triple ionization interface for ionizing sample components is provided. The ionization interface of the mass spectrometer includes a means for ionizing sample components via electrostatic ionization, atmospheric pressure chemical ionization, and laser diode thermal desorption.

Ion source for mass spectrometer

A mass spectrometer including a memory unit storing information indicating combinations of precursor ions for CIDs in respective stages. If an MSspectrum on which CID is not performed is obtained during execution of an analysis, a precursor ion selector determines whether an ion registered as a precursor ion for the first-stage CID exists on the MSspectrum, based on the list held in the memory unit. If the ion exists, an MSanalysis in which the ion is set as a precursor ion is immediately executed. Subsequently, the precursor ion selector determines whether or not an ion registered as a precursor ion for the second-stage CID in association with the precursor ion for the first-stage CID exists on an MSspectrum. If the ion exists, an MSanalysis in which the ion is set as a precursor ion is immediately executed, so that an MSspectrum is acquired.

Mass spectrometer

In a mass spectrometric method of the invention, a mass spectrometer () is used having a mass separation unit () before and after a collision cell () for fragmenting ions. When a product ion corresponding to a precursor ion set for a sample is selected by performing product ion scan with respect to the precursor ion, an exclusion range of mass-to-charge ratios is set based on information on non-selection ions input by a user, and a product ion that satisfies a predefined criterion is selected within a range of mass-to-charge ratios excluding the exclusion range in a product ion spectrum. According to the mass spectrometric method of the invention, product ions suited for measurement on a target compound can be selected.

Mass spectrometric method, mass spectrometer, and mass spectrometric data processing program

When setting analysis conditions, an analysis operator sets, on a dwell-time calculation/loop-time listing window, the target value of a loop time corresponding to the measurement-time interval to repeat an analysis for one ion, and clicks a dwell time calculation button. Then, a dwell time calculator computes the dwell time for each event, based on the target value of the loop time, the arrangement of events set at that point in time, the number of target ion species set in each event, and other conditional factors. The calculated result is displayed in a dwell time calculation result display field in a listing table. The largest and smallest values of the dwell time are displayed in the largest/smallest dwell time display field. The analysis operator checks this display and changes the target value of the loop time and/or the measurement time of the event so as to achieve an appropriate dwell time.

Growing community of inventors

Kyoto, Japan

Tairo Ogura