Zeon Corporation

Taichi Sawaguchi

Satoru Adachi

Nozomi Yabuki

Shigetaka Hayano

Koji Minami

Hironari Sudeji

Shinsuke Miyazawa

Daido Chiba

Kunihito Arai

Hideyuki Kanda

Satoshi Adachi

Yuki Nakama

Mitsukazu Aizawa

Noriyuki Aritome

Provided is a pre-filled syringe that can inhibit protein aggregation in a protein solution formulation while also reducing the produced amount of a decomposition product of a non-ionic surfactant after long-term storage. The pre-filled syringe includes: a barrel formed of a resin containing a hydrogenated cycloolefin ring-opened polymer and/or a copolymer of a cycloolefin and a chain olefin; a sealing member sealing a nozzle of the barrel; a gasket housed inside the barrel; and a plunger performing a movement operation of the gasket, and contains a protein solution formulation in a space defined by the sealing member, the gasket, and a region that is part of an inner wall surface of the barrel. The protein solution formulation has a non-ionic surfactant concentration of more than 0 mg/mL and less than 0.05 mg/mL.

Pre-filled syringe and method of producing pre-filled syringe

Provided is a hydrogenated ring-opened polymer having excellent ductility. The hydrogenated ring-opened polymer includes 90 mass % or more of norbornene-derived structural units. The proportion of meso diads of cis-structural units (I) of formula (I), shown below, included among the norbornene-derived structural units is not less than 0% and not more than 30% or is not less than 70% and not more than 100%. Trans-structural units (II) of formula (II), shown below, constitute a proportion of not less than 0.5% and not more than 20% among the total of the cis-structural units (I) of formula (I) and the trans-structural units (II) of formula (II).

Hydrogenated ring-opened polymer, resin composition, and shaped product

A method for handling a sample of a biochemical substance with a biochemical tool is provided. The method comprises a step of bringing the sample of the biochemical substance into contact with the biochemical tool. The sample of a biochemical substance includes nucleic acids. The biochemical tool comprises a part configured to contact the sample of the biochemical substance, the part being made of a resin composition containing at least one cycloolefin polymer selected from the group consisting of a copolymer of a cycloolefin and a chain olefin, a ring-opened polymer of a cycloolefin, and a hydrogenated product of a ring-opened polymer of a cycloolefin, and an antioxidant, the resin composition comprising 0.01 parts by mass or more and 0.7 parts by mass or less of the antioxidant relative to 100 parts by mass of the cycloolefin polymer.

Method for handling a sample of a biochemical substance with a biochemical tool

It is an object of the present disclosure to provide a biochemical tool capable of satisfactorily reducing absorption of a biochemical substance to a surface contacting a sample of the biochemical substance. A biochemical tool configured to contact a sample of a biochemical substance includes a part configured to contact the sample of the biochemical substance, the part being made of a resin composition containing at least one cycloolefin polymer selected from the group consisting of a copolymer of a cycloolefin and a chain olefin, a ring-opened polymer of a cycloolefin, and a hydrogenated product of a ring-opened polymer of a cycloolefin, and an antioxidant, the resin composition including 0.01 parts by mass or more and 0.7 parts by mass or less of the antioxidant relative to 100 parts by mass of the cycloolefin polymer.

Biochemical tool

Provided is a resin sheet including a plurality of aspheric sections having low variation of thickness precision and high shape precision. A method of producing a resin sheet includes hot press forming a thermoplastic resin film formed using a thermoplastic resin so as to produce a resin sheet including a plurality of aspheric sections that are separated from one another. The hot press forming is performed by increasing the pressing pressure to a final pressing pressure with an average pressure increase rate of 0.1 MPa/s or less at a pressing temperature that is at least 40&#xb0; C. higher than the glass-transition temperature of the thermoplastic resin.

Resin sheet and method of producing resin sheet

A medicine container which absorbs very little protein over time is manufactured using a resin composition including 50 to 99 wt % of a norbornene-based polymer, and 1 to 50 wt % of a hydrogenated styrene-based thermoplastic elastomer, a content of a low-molecular-weight component having a weight average molecular weight of 1000 or less in the resin composition being 3 wt % or less.

Resin composition and medical drug container using same

Disclosed is method of manufacturing a microchannel chip by joining together a resin channel substrate having microchannels formed on at least one side thereof and a resin lid substrate, the method including: a step (A) wherein surface modification treatment is applied on joining surfaces of the channel substrate and the lid substrate; and a step (B) wherein, after the step (A), the joining surfaces of the channel substrate and the lid substrate are mated and the channel substrate and the lid substrate are pressurized under heating via a fluid or an elastic body having a durometer hardness of E20 or less.

Method of manufacturing microchannel chip

The present invention is a three-dimensional modeling material containing an alicyclic structure-containing polymer and having a void fraction of 10 vol % or lower, a method for producing the three-dimensional modeling material, and a resin formed article obtained by a thermal melting lamination method using the three-dimensional modeling material. Though the present invention, there are provided a three-dimensional modeling material capable of obtaining a resin formed article having little warp and excellent in impact resistance and appearance, a production method therefor, and a resin formed article formed by using the three-dimensional modeling material.

Material for three-dimensional modeling, method for manufacturing material for three-dimensional modeling, and resin molded body

The present invention is a resin composition comprising a cycloolefin resin and at least two hydrogenated styrene-based thermoplastic elastomers, wherein a content of the cycloolefin resin is 50 to 90 wt % based on a total amount of the cycloolefin resin and the hydrogenated styrene-based thermoplastic elastomers, and a melt volume rate of the resin composition at 260&#xb0; C. is higher than that of the cycloolefin resin at 260&#xb0; C., and a resin formed article. One aspect of the invention provides a resin composition that exhibits excellent transparency, impact resistance and melt fluidity, as well as a resin formed article obtained by forming this resin composition. The resin formed article of the present invention is preferably used as a drug container, a medical instrument or the like, since it exhibits excellent transparency and impact resistance.

Resin composition and resin molded article

A resin composition includes an alicyclic structure-containing polymer; a hindered amine compound; and a releasing agent, wherein the releasing agent and the alicyclic structure-containing polymer satisfy the following relationship: 10&#x2267;|s1&#x2212;s2|&#x2267;0.8 [(MPa)], wherein s1 represents a solubility parameter of the releasing agent, and s2 represents a solubility parameter of the alicyclic structure-containing polymer. The resin composition can be used as optical materials, such as a lens, a diffraction grating, and a prism, especially in the field of using blue laser, and has excellent releasability, transparence and colorless property as well as excellent resistance to laser.

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Tokyo, Japan

Taichi Sawaguchi