University of Illinois

Taewoo Kim

Gabriel Popescu

Paul Scott Carney

Lynford L Goddard

S Derin Babacan

Mustafa A H Mir

Renjie Zhou

Methods and a module for use with a microscope for enhancing image contrast in an image of a phase object. A transmission image of a specimen is formed in an image plane, of which a Fourier transform is generated in a Fourier plane. An amplitude filter is applied to the Fourier transform field, which is then transformed back to an image at a focal plane of a detector array. An image signal from the detector array is processed to generate a contrast-enhanced image of the specimen.

Phase derivative microscopy module having specified amplitude mask

Methods for obtaining a tomographic phase image of a specimen, either in transmission or in scatter. A specimen is illuminated by a temporally incoherent source and light collected in transmission or scattering is used to generate a scattered phase image of the specimen in multiple axial planes. The scattered field is solved for in wavevector space, and a derived instrument function is deconvolved to obtain specimen susceptibility in wavevector space. The specimen susceptibility is transformed to obtain a three-dimensional phase tomogram of the specimen.

White light diffraction tomography of unlabeled live cells

Growing community of inventors

Urbana, IL, United States of America

Taewoo Kim