Samsung Electronics Co., Ltd.

Seoul National University

Sk Telecom Company, Ltd.

Snu Rdb Foundation

Taesung Park

Choongbin Yim

Sangjo Han

Yonghwan Choi

Sung Gon Yi

Junghyun Namkung

Jin-Young Jang

Jin-Woo Park

Youngsoo Kim

Seokhyun Lee

Hae-Jung Yu

Yongsoo Kim

Yoon-Keun Kim

Sung-young Lee

Su-hyeon Kim

Tae-Jin Ahn

SoYeon Ahn

Hyeongmun Kang

Eunchul Ahn

Sung-ho Won

Seung-yeoun Lee

Bora Yeon

Taegyun Yun

Young-ho Park

Se Ik Kim

Yong Sang Song

Sanjo Han

The present invention relates to a method of diagnosing ovarian cancer through microbial metagenomic analysis, and more particularly to a method of diagnosing ovarian cancer by analyzing an increase or decrease in content of specific bacteria or archaea-derived extracellular vesicles through metagenomic analysis using a subject-derived sample. Extracellular vesicles secreted from microorganisms existing in the environment are absorbed into the human body, and thus may directly affect the occurrence of cancer, and it is difficult to diagnose ovarian cancer early before symptoms thereof so that efficient treatment thereof is difficult. Thus, according to the present invention, a risk for ovarian cancer can be predicted through metagenomic analysis of bacteria-derived extracellular vesicles using a human body-derived sample, and thus the onset of ovarian cancer can be delayed or ovarian cancer can be predicted through appropriate management by early diagnosis and prediction of a risk group for ovarian cancer, and even after ovarian cancer occurs, early diagnosis for ovarian cancer can be implemented, thereby lowering the incidence of ovarian cancer and increasing therapeutic effects.

Method for diagnosing ovarian cancer through microbial metagenome analysis

A composition, for diagnosing the possibility of onset of pancreatic cancer including an agent measuring the expression level of marker protein of diagnosing the possibility of onset of pancreatic cancer, or mRNA expression level of a gene encoding the protein, a kit including the composition, and a method of diagnosing pancreatic cancer using the maker are provided. The diagnostic markers of pancreatic cancer in accordance with the present disclosure are useful for predicting or diagnosing the onset, the possibility of onset, and the severity of pancreatic cancer in an early stage, and are also applied to a study on the tumorigenesis of pancreatic cancer. In addition, the diagnosis method of the present invention allows for the convenient detection of pancreatic cancer in a non-invasive manner in a sample such as blood.

Composition for diagnosing pancreatic cancer and method for diagnosing pancreatic cancer using same

The present invention relates to: a composition for diagnosing pancreatic cancer, containing a preparation for measuring the expression level of a protein or a gene thereof, and capable of being used for determining whether there is a risk of pancreatic cancer; a kit; and a method for diagnosing pancreatic cancer by using the same. The present invention can significantly predict or identify the risk of pancreatic cancer or a precancerous lesion of pancreatic cancer, the early diagnosis thereof and the extent of diseases thereof by providing a diagnostic marker of pancreatic cancer, and can be utilized in the research of pancreatic cancer oncogenesis. In addition, the diagnostic method of the present invention can provide simple and early diagnosis of pancreatic cancer from the blood and the like in a non-invasive manner.

Composition for diagnosing pancreatic cancer and method for diagnosing pancreatic cancer using the same

A package-on-package (POP) electronic device may include first and second packaging substrates, a solder interconnection providing electrical and mechanical coupling between the first and second packaging substrates, and first and second sealing layers between the first and second packaging substrates. The first and second sealing layers may be respective first and second epoxy sealing layers. Moreover, the second epoxy sealing layer may include a solder flux agent, and the first epoxy sealing layer may have a lower concentration of the solder flux agent than the second epoxy sealing layer.

Package-on-package electronic devices including sealing layers and related methods of forming the same

Stacked semiconductor chips include a bonding-wire-free interconnection electrically connecting the semiconductor chips to each. An opening in an adhesion layer between the semiconductor chips may provide a path for the interconnection from a bonding pad on one semiconductor chip, along a sidewall insulation layer of the semiconductor chip, along a sidewall insulation layer of another semiconductor chip to a bonding pad on the other semiconductor chip.

Method and apparatus for stacked semiconductor chips

A semiconductor package, comprising: a semiconductor substrate; a mold layer on the semiconductor substrate; and a marking formed on a surface of the mold layer, the marking comprising dot markings substantially discontinuously arranged in vertical and horizontal directions of a display region. An effective area of the dot markings within a unit display region of the marking is smaller than about half a total area of the unit display region.

Semiconductor package and method of fabricating the same

Apparatus for stacked semiconductor chips

A method of recovering a nucleic acid sequence using a probe map includes: aligning a probe onto a target sequence based on a result in which the probe is hybridized to the target sequence; determining a representative value representing each aligned position of the probe; and recovering a base sequence of the target sequence by using a probe map to which the determined representative values and base sequence information of the probe are mapped.

Method and apparatus for recovering gene sequence using probe map

Growing community of inventors

Cheonan-si, South Korea

Taesung Park