Sk Chemicals Co., Ltd.

Taekyung Yoo

Jae-Sun Kim

Jaeseung Ahn

Min-Young Han

So-young Lee

Ju Young Lee

Bong-Yong Lee

Hun-Taek Kim

Je Ho Ryu

Jung A Lee

Seon-Mi Kim

Young-Ah Shin

Young Ah Shin

Joon Ho Sa

Minhee Lee

Euisun Park

Jeong A Lee

Jeongmin Seo

So-Young Lee

The present invention relates to: a compound selected from the group consisting of a tricyclic compound having the structure of formula I, a pharmaceutically acceptable salt, an isomer, a solvate and a precursor thereof; and a use thereof. The compound effectively controls GPR40, and thus, can be effectively used for the prophylaxis or treatment of diseases associated with GPR40, for example, diabetes and many other diseases.

Tricyclic compound and use thereof

Disclosed are a gonadotropin releasing hormone receptor antagonist and a pharmaceutical composition including the same, which can be useful in preventing or treating a sex hormone-related disease such as endometriosis, amenorrhea, irregular menstruation, uterine myoma, uterine fibroids, polycystic ovarian disease, lupus erythematous, hypertrichosis, precocious puberty, short stature, acne, alopecia, gonadal steroid-dependent neoplasms, gonadotropin-producing pituitary adenoma, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hyperplasia, contraception, and infertility, as well as Alzheimer disease.

Gonadotropin releasing hormone receptor antagonists, method for the preparation thereof and pharmaceutical composition comprising the same

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Uiwang-si, South Korea

Taekyung Yoo