Lg Electronics Inc.

Korea Institute of Science and Technology

The Industry & Academic Cooperation in Chungnam National University

Dreambiogen Co., Ltd.

Taek Chan Kang

Dong-Myung Kim

SAng Hyeon Kang

Gyo Chang Keum

Hee Won Jin

Seung Woo Cho

Sang Kil Lee

Eun Kyoung Bang

Cha Yong Choi

Ki Baek Lee

Ji Hyoung Woo

Ashraf Kareem El-Damasy

Ho-Cheol Kim

Disclosed are a compound selected from novel indazole derivatives, pharmaceutically acceptable salts thereof, hydrates thereof and stereoisomers thereof, a method for preparing the compound, and a pharmaceutical composition for preventing, alleviating or treating cancer containing the compound as an active ingredient. The novel indazole derivatives exhibit excellent ABL/DDR1 inhibitory efficacy and anti-proliferative efficacy against cancer cells, specifically blood cancer cells, and inhibitory activity against ABL T315I point mutations, thus being useful for the prevention, alleviation or treatment of cancer, specifically blood cancer, especially chronic myelogenous leukemia.

Indazole derivatives and pharmaceutical composition for preventing, alleviating or treating cancer containing the same

A method for cell-free protein synthesis is characterized in that pH is controlled by using an enzyme. For example, by using an amino acid decarboxylase, the pH is controlled according to removal of hydrogen ions that are produced during regeneration of ATP. The method for cell-free protein synthesis of the present invention has an advantage that not only the expression amount of protein is enhanced but also the expressed protein can be directly used for activity analysis without undergoing any separation or purification.

Method for cell-free protein synthesis involved with pH control with amino acid decarboxylase

A system for limiting access to a mobile communication terminal comprises user interface for providing an option to select an authentication method to lock the mobile communication terminal; and memory for storing a plurality of lock codes, including image lock codes, inputted into the mobile communication terminal for locking the mobile communication terminal.

Method and system for controlling access to a mobile communication terminal

The present invention relates to methods of production of the completely post-translationally modified protein by combination of cell-free protein synthesis and cell-free co- and post-translational modification. Previous cell-free protein synthesis system has only been capable of producing partially post-translationally modified protein but the present invention employs a co- and post-translational modification machinery that produces completely post-translationally modified protein.

Method for cell-free protein complete post-translational modification

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Seoul, South Korea

Taek Chan Kang