Kobiolabs, Inc.

Research Cooperation Foundation of Yeungnam University

Tae Wook Nam

Gwang Pyo Ko

In Su Kim

Jin Woo Lee

Hye Jin Kim

June Chul Lee

Woon Ki Kim

Woo Ri Ko

Dae Hee Han

Hyo In Park

Hyun Ju You

Byeong Seon Jeong

You Ra Kang

Jung Ae Kim

Hyo Shin Yoon

Chung Hwan Cho

Jin Mo Ku

Ned A Porter

The present invention relates toSNUG-61027 strain (accession number KCTC 13530BP) and use thereof, specifically, a composition for suppressing appetite or preventing, ameliorating, alleviating or treating metabolic diseases, comprising the strain, or a culture solution thereof, etc. or a B2UM07 protein isolated therefrom as an active ingredient, and use thereof for suppressing appetite or preventing, ameliorating, alleviating or treating metabolic diseases, and a method of suppressing appetite or preventing, ameliorating, alleviating or treating metabolic diseases using the same are provided. Through this, among the anti-obesity effects, not only weight reduction and glucose homeostasis regulation, but also the effect on brown fat and the effect of secreting appetite regulating hormones are exhibited.

strain and use thereof

A strain ofKBL697 and the use thereof are described. The strain ofKBL697 (Accession No. KCTC 13520BP) attenuates allergic reactions of cells, significantly improves symptoms of atopic dermatitis, and exhibits anti-inflammatory and anti-fungal effects and a therapeutic effect for intestinal diseases such as irritable bowel syndrome and colitis. Thus, the single strain alone can achieve all the purposes of alleviating allergic diseases and inflammatory diseases and improving intestinal health, thereby finding advantageous applications as a probiotic substance. In addition, the strain, based on the anti-fungal activity thereof, can be advantageously utilized in a skin external preparation against various skin diseases caused by fungi, and in a cosmetic composition and a functional patch for alleviating sensitive skin.

Lactobacillus Gasseri KBL697 strain and use thereof

KBL697 strain and use thereof

Disclosed is a pharmaceutical composition including a bicyclic pyridinol derivative as an active ingredient for preventing or treating diseases caused by angiogenesis. The bicyclic pyridinol derivative expressed by Chemical Formula 1 can be effectively used as a drug for preventing and treating diseases caused by angiogenesis since it inhibits neovascularization in a chorioallantoic membrane model.

Pharmaceutical composition comprising bicyclic pyridinol derivatives for preventing or treating diseases caused by angiogenesis

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Gyeonggi-do, South Korea

Tae Wook Nam