Konkuk University Industrial Cooperation Corp

Intelligent Synthetic Biology Center

Tae-Su Kim

Jung-Kul Lee

Ji-Hyun Park

Sun-Chang Kim

Jinglin Li

Chandra Sujan Sigdel

Ranjitha Ramakrishnan

The present invention relates to improving the enzymatic activity ofO157:H7-derived sugar isomerase by molecular mechanics and site-directed mutagenesis. More particularly, the present invention relates to a sugar isomerase having an enzymatic activity improved by mutation, a nucleic acid molecule encoding the same, a vector comprising the nucleic acid molecule, a transformant comprising the vector, a mutant of the sugar isomerase, and a method for producing L-gulose using the improved sugar isomerase.

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This invention relates to a novel formaldehyde dehydrogenase expressed by a formaldehyde dehydrogenase gene and having independent reduction activity for formic acid, a method of preparing the formaldehyde dehydrogenase from a strain transformed with a recombinant expression vector including the gene, and a method of producing formaldehyde from formic acid through a reduction reaction of the formaldehyde dehydrogenase.

Formaldehyde dehydrogenase and method for preparing formaldehyde using same

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Seoul, South Korea

Tae-Su Kim