Korea Research Institute of Bioscience and Biotechnology

Korea Institute of Science and Technology

Korea Research Institute of Chemical Technology

Tae Sook Jeong

Ho Yong Park

Kwang Hee Son

Young Kil Kim

Sung Uk Kim

Jae Sun Moon

Song H Bok

Sung U Kim

Hang W Lee

Sang Ho Choi

Myung-Sook Choi

Sang Han Lee

Seong Kyun Kim

Byoung Mog Kwon

Mun-Chual Rho

Dong-Ha Shin

Sangku Lee

Han-Young Cho

Soo Yong Kim

Jee W Lee

Yong K Kwon

Ingyu Hwang

Byoung-Keun Park

Ju Ryoung Kim

Seungeun Kim

Hyeon-Seon Ji

Eui Il Hwang

Hye K Kwon

Rosales Ovares Kattia

Hua Li

Zamora Villalobos Nelson

Hwa Lee

The present invention relates to a cosmetic composition for preventing skin aging and reducing skin wrinkles containing an extract of-The cosmetic composition has an excellent antioxidant effect and exhibits the effect of inhibiting collagenase overexpression and increasing collagen gene expression, and thus can be effectively used for the purposes of preventing skin aging and reducing skin wrinkles.

Cosmetic composition for preventing skin aging and reducing skin wrinkles, comprising Viburnum stellato-tomentosum extract

A composition for prevention or treatment of metabolic syndrome or for antioxidation includes black soybean leaf extracts and flavonol glycoside compounds isolated thereof as active ingredients. It has been confirmed that the black soybean leaf extracts and the flavonol glycoside compounds isolated thereof effectively inhibit &#x3b1;-glucosidase activity; LDL oxidation and DDP-4; have excellent DPPH radical scavenging activity; inhibitory activity of reactive oxygen species (ROS) accumulation; effectively promote insulin secretion; regulate the expression of major genes; have an excellent ability to reduce a waist/hip circumference ratio; decrease the concentrations of plasma free fatty acid and plasma triglyceride; increase the concentration of plasma HDL-cholesterol; decrease an atherogenic index; increase erythrocyte catalase, SOD and GR activities; decrease erythrocyte lipid peroxide TBARS; decrease the concentrations of inflammatory cytokines MCP-1 and PAI-1, and resistin; and increase the concentration of plasma adiponectin.

Composition for prevention or treatment of metabolic syndrome or for antioxidation containing black bean leaf extracts and flavonol glysosides isolated therefrom as active ingredients

The present invention relates to novel iturin biosynthesis genes, and uses thereof. More specifically, the present invention provides novel iturin biosynthesis genes, wherein the iturin biosynthesis genes were cloned fromsubsp.ATCC 55079, the base sequence was determined after checking whether the cloned genes are iturin biosynthesis genes or not, and it was ascertained that the identified genes are novel genes different from the reported gene by comparing the base sequences with that of the reported gene, and uses thereof.

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The present invention relates to a pharmaceutical composition and health food comprisingsp. PL3 extract or phellinsin A isolated from the same as an effective component. More particularly, the present invention relates to a pharmaceutical composition and health food comprisingsp. PL3 extract or phellinsin A isolated from the same as an effective component, wherein thesp. PL3 extract and its phellinsin A inhibit the oxidation of low density lipoprotein (LDL), and further, they can be used as a component for medicine and food to effectively prevent and treat cardiovascular diseases such as hyperlipemia and arteriosclerosis.

A novel ACAT inhibitor of formula (I) useful for the treatment of hyperlipidemia produced from Aspergillus fumigatus FM-F-37; derivatives of said ACAT inhibitor, which are separated from the culture of A. fumigatus FM-F-37 or prepared by a chemical process, also possess ACAT inhibition property. ##STR1##

Acyl CoA:cholesterol acyltransferase inhibitors

The present invention provides a novel microorganism, Bacillus subtilis subspecies Krictiensis, and its mutant, Bacillus subtilis subspecies Krictiensis M 18-91; and a novel antifungal complex, KRF-001, produced from said microorganisms. The present invention also provides a process for producing said complex by culturing or fermenting said microorganisms and a process for purifying said complex to a desired degree of high purity.

Culture of Bacillus subtilis

Growing community of inventors

Daejeon, South Korea

Tae Sook Jeong