Amorepacific Corporation

Snu Rdb Foundation

Tae Ryong Lee

Hyoung June Kim

Ji Hyun Kim

Hyun Yeul Lee

Jon Hwan Lee

Jaeyoung Ko

Jaewon You

Han Bit Kim

Sung Tae Kim

Sun Young Park

Hyun Jung Choi

Yonghee Lee

Hae Kwang Lee

Eun Kyung Lee

Ji Young Lee

Yong Jin Kim

Sang Jun Lee

Young Gyu Kang

Eui Seok Shin

Seung Hyun Shin

Eun-Gyung Cho

Pil Joon Park

Kyeonghwan Hwang

Ji Yeon Han

Won Seok Park

Jin Oh Chung

Jin Sup Shim

Bum Jin Lee

Jin Ho Chung

Sung Won Yi

Ga Young Cho

So Hee Lee

Eun Gyung Cho

Il Young Kwack

Hak Hee Kang

Jeong Eun Seo

Yu Jin Oh

Seung Han Park

Hui Kyoung Chang

Dae Jin Min

Byung Guen Chae

Sung Hoon Lee

Eui Dong Son

Dong Wook Shin

Eun-Jeong Choi

Kyu Han Kim

Bum Ho Bin

Il Hong Bae

Hyeon Chung Kim

Jong Hwa Park

Young Kyung Kim

Hyunjung Choi

Seong A Cho

Kyung Hee Suh

Byeong Bae Jeon

Hyoung-June Kim

Gae Won Nam

Eun Jeong Choi

Bum-Ho Bin

Suh-Yeon Choi

Yunghyup Joo

Young Oh Lee

Hyun Hyub Ko

Jin Young Myoung

Yu Chul Jung

Ju Yearl Park

Min Sik Choi

Min Jung Chae

Myeong Jin Goh

Jue Won Kim

Seon Pil Jin

Gibaeg Nam

Wanil Kim

Joong Hyun Shim

Seung Ha Yang

Ji Yong Jung

Eungyung Cho

Eunkyung Lee

Hyun Gee Lee

Il-Hong Bae

Hyun Woo Park

Ji Young Chun

Yoo Kim

Provided are a composition including a compound of the following chemical formula as an active ingredient, and a method of enhancing a skin barrier by applying it to the skin:

Composition and method of enhancing skin barrier using the same

A sensor for measuring a temperature change amount. The sensor includes a first composite material layer including a polymer having a volume changing according to a temperature change amount; an electrode layer provided on one side of the first composite material layer and capable of representing the temperature change amount as a resistance change amount; and a second composite material layer at least partially provided on the upper side of the first composite material layer and containing polydimethylsiloxane (PDMS) and at least one of carbon nanotubes (CNT), boron nitride nanotubes (BNNT), and graphene or containing a thermoplastic polyurethane (TPU) so that the temperature change occurring on one side thereof is transferred to the other side thereof.

Sensor for measuring temperature change amount

The present specification relates to an adamantanecarboxylic acid benzyl amide derivative compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, and a skin whitening composition comprising the same as an active ingredient. Specifically, the compound, according to the present specification, is a compound having a novel structure having adamantanecarboxylic acid bound to an amine compound, and exhibits a skin whitening effect by inhibiting the production of melanin, and thus may be used in various ways as a pharmaceutical composition, a cosmetic composition or a skin preparation for external use.

Adamantanecarboxylic acid benzyl amide derivative compound and skin whitening composition comprising same

The present specification discloses an immunomodulatory composition comprising lactobacillus-derived extracellular vesicles as an active ingredient. The lactobacillus may be. The composition has the effects of inducing differentiation into M2-type macrophages and reducing expression of at least one member selected from the group consisting of CCR2, SOCS3 and HLA-DR&#x3b1;, which are M1-type macrophage differentiation markers.

Immunomodulatory composition comprising lactobacillus-derived extracellular vesicles

A cosmetic composition includes a compound of the following chemical formula as an active ingredient. A method for regenerating skin includes applying an effective amount of the cosmetic composition to skin: 

Cosmetic composition for skin regeneration

Disclosed is a composition including aextract as an effective ingredient for treating fine dust-caused skin damage, wherein the expression of at least one selected from the group consisting of IL-36G (NM_019618), PTGS2 (NM_000963), XDH (NM_000379) and S100A7 (NM_002963), which are all genes having the expression levels affected by fine dust in skin cells, is regulated to a normal level and for inhibiting an antibacterial peptide, wherein the expression of the antibacterial peptide S100A7 (NM_002963) is regulated to a normal level. By using the composition for treating fine dust-caused skin damage and the composition for inhibiting an antibacterial peptide, gene expression changed by fine dust can return to a normal level to treat skin cell damage and the increased expression of the antibacterial peptide due to various causes can return to normal level.

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A skin external composition containing 1,2,3,4,6-penta-O-galloyl-&#x3b2;-D-glucose (hereinafter referred to as 'PGG') and its use to improve moisture balance of skin are disclosed. The skin external composition, due to containing PGG, stimulates the formation of filaggrin in keratinocytes, increases loricrin and involucrin expression, thereby stimulating the formation of a normal keratin layer, and as a result, can strengthen the skin barrier function to provide an excellent skin moisturization improving effect. Thus, the composition is effective in improving moisture balance of skin. A method for moisturizing the skin using the composition is also disclosed.

Skin external preparation composition for moisturizing skin containing 1,2,3,4,6-penta-O-galloyl-&#x3b2;-D-glucose

Disclosed is a novel use of a composition comprising as an active ingredient anextract. A composition according to the present description shows hair follicle cell proliferation or hair growth effect by means of comprising anextract. Therefore, due to said effect, theextract has hair loss prevention or hair growth stimulation effect.

Composition for hair loss prevention or hair growth stimulation comprisingextract

Provided in the present invention are adult stem cells derived from human skin dermis, and a method for isolating same. Further provided in the present invention are osteoblastic cells and adipocytes differentiated from the adult stem cells derived from human skin dermis, and a differentiation method therefor. Further provided in the present invention is a composition for osteogenesis or lipogenesis containing the stem cells, osteoblastic cells, or adipocytes. The isolation method of the present invention enables the adult stem cells derived from human skin dermis to be obtained in an easy and simple manner at a high yield rate. Genes and growth factors which are specifically expressed in the adult stem cells derived from human skin dermis isolated using the method can be separated, identified, and used later.

Adult stem cells derived from human skin dermis

The present specification discloses a composition for preventing hair loss or promoting hair growth comprising, as an active ingredient, extracellular follicles derived from lactic acid bacteria, and a method for preparing the extracellular follicles derived from lactic acid bacteria. The composition has an effect of preventing and prohibiting hair from falling off from the scalp or becoming thin or tapered. In addition, the composition has an effect of implementing a hair growth function for generating new hair, or a function for promoting the hair growth, as well as a function of promoting a delay from an anagen to a catagen phase of a hair cycle and a function of growing the existing hair healthy.

Composition for preventing hair loss or promoting hair growth comprising extracellular follicle derived from lactic acid bacteria

Disclosed in the present specification are: a composition for preventing hair loss or promoting hair growth, containing-derived exosome-like vesicles; and a method for preparing the composition. The-derived exosome-like vesicles can have a diameter of 20-500 nm and can be isolated fromroot. The composition contains-derived exosome-like vesicles as active ingredients, thereby having an effect of inducing hair growth by activating dermal papilla cells (DPCs).

Composition for preventing hair loss or promoting hair growth, containing ginseng-derived exosome-like vesicles

Disclosed are: a lightening composition comprising ginseng-derived exosome-like vesicles; and a method for producing the ginseng-derived exosome-like vesicles. The ginseng-derived exosome-like vesicles may have a diameter of between 20 and 500 nm, and may be isolated from ginseng root. Because the composition comprises the ginseng-derived exosome-like vesicles as an active ingredient, said composition is effective in preventing, improving or treating skin pigmentation conditions such as liver spots, freckles, lentigo, birth marks and melanoma by effectively suppressing the production of melanin.

Lightening composition comprising ginseng-derived exosome-like vesicles

Disclosed is a novel use of a composition comprising as an active ingredient aextract. A composition according to the present description shows hair follicle cell proliferation or hair growth effect by means of comprising aextract. Therefore, due to said effect, theextract has hair loss prevention or hair growth stimulation effect.

Unlike a conventional method for evaluating a degree of ultraviolet protection through visual evaluation, the disclosed method for measuring a sunlight protection function can accurately and objectively measure and determine a degree of sunlight protection by measuring a change due to a material to be measured with respect to an expression amount of skin tissue antimicrobial peptides (AMPs) in skin cells, which decrease from exposure to sunlight, and/or a generation amount of S-nitrosylated protein. Additionally, the disclosed measurement method can determine whether blue/violet light of wavelengths of 400-500 nm, which induces the most skin damage among visible rays, is blocked and provide a more specified sunlight protection effect evaluation result. Moreover, by using the disclosed measurement method, a degree of sunlight protection can be indexed, and a sunlight protection composition for protecting normal skin from the blue/violet light can be provided.

Method for screening for sunlight protection functional material and method for evaluating sunlight protection effect

The present invention relates to novel melanocytes and melanoblasts. In addition, the present invention relates to a novel method for producing melanocytes and melanoblasts. Specifically, provided is novel melanocytes of which gene expression, melanin content, and tyrosinase activity are different from those of conventional melanocytes. Even more specifically, provided is novel melanoblasts of which the gene expression, the melanin content the tyrosinase activity, and the protein expression are different from those of conventional melanocytes. Additionally, provided is a novel method for producing melanocytes or melanoblasts by culturing keratinocytes.

Melanocyte or progenitor cell thereof adapted to keratinocyte, and preparation method thereof

Growing community of inventors

Yongin-si, South Korea

Tae Ryong Lee