Fuji Yakuhin Kogyo Kabushiki Kaisha

National Federation of Agricultural Cooperative Associations

Daiichi Fine Chemical Co., Ltd.

Nitto Denko Co. Ltd.

Tadashi Takeuchi

Kenji Mori

Masakazu Aburatani

Shuji Senda

Tetsuo Omata

Yasuo Ninomiya

Miklos Toth

Noriaki Murata

Atsunori Aramata

Michimasa Watanabe

Yuhki Takeuchi

Takahiro Isobe

Hans-Rudolf Buser

Heinrich Arn

A compound represented by the following general formula (I): [wherein Rrepresents hydrogen atom, or an alkyl group, Rrepresents a hydroxyalkyl group, or a triarylmethyloxyalkyl group, or Rand Rcombine together to represent &#x2014;C(R)(R)&#x2014; (Rand Rrepresent hydrogen atom, an alkyl group, or hydroxyl group, or Rand Rmay combine together to represent oxo group), or &#x2014;C(R)(R)&#x2014;O&#x2014;C(R)(R)&#x2014; (Rto Rrepresent hydrogen atom, an alkyl group, or hydroxyl group, or Rand Rmay combine together to represent oxo group, and Rand Rmay combine together to represent oxo group); Arto Arindependently represent an aryl group (the aryl group may have 1 to 5 of the same or different substituents), *1 to *4 indicate asymmetric carbons, and configurations are cis between *1 and *2, cis between *3 and *4, and trans between *2 and *3]. An optically active phosphine ligand which can be easily synthesized and gives a transition metal complex showing superior asymmetric catalyst activity is provided.

Bisphosphine ligand

A hydroxy-1-alkyne is reacted with a tin hydride compound, and the obtained (E,Z)-hydroxyvinylstannanes are separated to give the (E)-substance which is further converted to a vinylcopper complex shown by

Process for the preparation of prostaglandins

6,6-Ethylenedioxy-22R-hydroxy-2R,3S-isopropylidenedioxy-5.alpha.-cholest-23 -yne, useful as an intermediate for the synthesis of brassinolide.

6,6-ethyl

The present invention provides mainly (3Z,6Z)-cis-9,10-epoxy-1,3,6-heneicosatriene (formula 1) and (3Z, 6Z)-cis-9,10-epoxy-1,3,6-elcosatriene (formula 2) which are Hyphantria cunea sex pheromones. The invention provides attractant components having high attraction effect for Hyphantria cunea, that is, Hyphantria cumea sex pheromones having high attraction activity and the intermediates which can selectively synthesize such pheromones with great ease. Furthermore, the invention provides attractant compositions with high attraction effect for Hyphantria cunea including such above noted pheromones. Consequently, this invention is completed. ##STR1##

Hyphantria cunea sex pheromones and attractant compositions including

New steroid compounds of the general formula: ##STR1## wherein X is a hydroxyl group and Y is a hydrogen atom, or X and Y, taken together, form an oxo group; each of the two R' radicals is independently a hydrogen atom, acyl group, a silyl group, an alkoxycarbonyl group or a benzyl group, or the two R' radicals, taken together, form an alkylidene or a carbonyl group, the stereo-configuration at the 22- and 23-positions being either 22R and 23R or 22S and 23S; and R' and R'' are independently of each other a hydrogen atom or a lower alkyl group, as well as processes for preparing same. These new steroid compounds are valuable intermediates for brassinolide and its analogues useful as plant hormones.

3.alpha.,5-cyclo-22,23-dihydroxy-5.alpha.-steroid compounds

Growing community of inventors

Toyama, Japan

Tadashi Takeuchi