The University of Toyama

Nissan Chemical Industries Limited

Nissan Chemical Corporation

Osaka Organic Chemical Industry Co., Ltd.

Tadashi Nakaji

Hiromi Kitano

Takahiro Kishioka

Yuki Usui

Taito Nishino

Yoshiomi Hiroi

Shigeo Kimura

Yoshiyuki Saruwatari

Kazuyoshi Matsuoka

Makoto Gemmei

Chirag Harsharan Singh Gujral

Provided are a ligand-bearing substrate which has a surface at least partially coated with a polymer (P3) containing structural units represented by the formulae (1) and (1) (in the formulae, R, R, X, Y, L, Q, Q, Q, m1, m2 and n are as described in the claims and description); a raw material for such a substrate; and a method for producing such substrates.

Substrates coated with selective cell separation or cell culture polymers

Disclosed are a cell culture substrate that can be modified from its cell-inadhesibleness to make it cell-adhesible, by a convenient and low-cost treatment, and particularly, a substrate that allows position-specific culture of one or more kinds of cells. The substrate has on its surface a layer made of a photomodifiable polymer that comprises a monomer, as component (A), represented by Formula (1): 

Material for cell patterning use

There is provided a new material that can form a finer pattern and can be applied to adsorption/adhesion control of various cell species, proteins, viruses, and the like without the limitation of the light source. A light-degradable material comprising: a moiety that is capable of bonding to a surface of a substrate through a siloxane bond; and a structural unit of Formula (2-a) and/or Formula (2-b): (where Rto Rare saturated linear alkyl groups; X is a hydrogen atom or an alkyl group; Z is a carbanion or a sulfo anion; Q is an ester bond group, a phosphodiester bond group, an amido bond group, an alkylene group, or an phenylene group or a combination of these divalent groups; mis an integer of 1 to 200, and n is an integer of 1 to 10).

Light-degradable material, substrate, and method for patterning the substrate

A composition for controlled release of a physiologically active substance can release a physiologically active substance in vivo at the desired timing. The composition includes an inner layer that is formed of a biodegradable substance that supports a physiologically active substance, and an outer layer that is formed of a biodegradable substance that differs from that of the inner layer.

Composition for controlled release of physiologically active substance

Growing community of inventors

Toyama, Japan

Tadashi Nakaji