Kuraray Noritake Dental Inc.

Tadashi Hashimoto

Koichi Okada

Mitsunobu Kawashima

Shumei Ishihara

Takahiro Sekiguchi

Mariko Sugiura

A method for inhibiting dentinal hypersensitivity by applying a dentinal hypersensitivity inhibitor on a dentin surface. The dentinal hypersensitivity inhibitor contains at least one tetracalcium phosphate particle, an alkali metal salt of phosphoric acid, and at least one acidic calcium phosphate particle. The tetracalcium phosphate particle has an average particle diameter of 0.5 to 40 &#x3bc;m. The dentinal hypersensitivity inhibitor contains a blended amount of the tetracalcium phosphate particle of 5 to 55 parts by weight relative to 100 parts by weight of a whole amount of the dentinal hypersensitivity inhibitor and a blended amount of the alkali metal salt of phosphoric acid of 1 to 100 parts by weight relative to 100 parts by weight of the tetracalcium phosphate particle.

Method for inhibiting dentinal hypersensitivity

A calcium phosphate composition comprising tetracalcium phosphate particles (A), calcium hydrogen phosphate particles (B) and at least one kind of inorganic particles (C) selected from silica particles or titania particles, wherein the mixing ratio (A/B) of (A) to (B) is from 45/55 to 55/45 in molar ratio, the inorganic particles (C) have an average particle diameter of from 0.002 to 0.5 &#x3bc;m, and the inorganic particles (C) are contained in an amount of 0.1 to 20 parts by weight based on 100 parts by weight of (A) and (B) in total. Thereby provided is a calcium phosphate composition such that when it is used as a material for bone repair, a formed bone has high mechanical strength and a high bone replacement rate is achieved.

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Kurashiki, Japan

Tadashi Hashimoto