Chugai Seiyaku Kabushiki Kaisha

Tadao Yamazaki

Hiroshi Nagai

Toshiari Morita

Yasushi Sato

Akihiko Saito

Tsutomu Arakawa

Akira Hayasaka

Masaya Kakuta

Hiroko Konishi

Yoshiki Hayashi

The present invention provides stabilized preparations containing an antibody in a glycine buffer and/or a histidine buffer and also provides processes for preparing a protein-containing stabilized preparation, comprising adjusting the pH with a basic amino acid or a basic amino acid derivative or a salt thereof.

Stabilized anti-interleukin-6 antibody-containing preparations

A stabilized antibody-containing preparation containing acetyltryptophan or an acetyltryptophan derivative or a salt thereof as a stabilizer for controlling the decrease in the biological activity of the antibody.

Stabilized preparations containing antibody

A stable protein formulation containing tryptophan or a tryptophan derivative or a salt thereof as a stabilizer.

Long-term stabilized formulations

This invention provides an erythropoietin solution preparation containing an amino acid as a stabilizer, and having excellent long-term storage stability.

Growing community of inventors

Shizuoka, Japan

Tadao Yamazaki