Kaneka Corporation

Tadao Ono

Yasuyoshi Ueda

Takahiro Ueda

Shiro Kitamura

Mitsutoshi Moro

Kenji Fujii

Kazunori Hosoe

The present invention provides a stabilization method, a preservation method and the like method of reduced coenzyme Q, which is useful as functional nutritive foods, specific health foods and the like. Furthermore, the present invention provides a method for efficiently obtaining reduced coenzyme Qof high quality and by a method suitable for a commercial production. It is possible to handle and stably preserve reduced coenzyme Qunder a condition that oxidation by a molecular oxygen is inhibited by contacting reduced coenzyme Qwith, an ascorbic acid and citric acid or a related compound thereof, and thus a stabilized composition is obtained. Moreover, reduced coenzyme Qis converted into a crystalline state in such a condition that the formation of oxidized coenzyme Qas a byproduct is minimized by crystallizing reduced coenzyme Qin the presence of ascorbic acid or a related compound thereof etc., and thus a reduced coenzyme Qcrystal of high quality is produced. Furthermore, by successively crystallizing the generated reduced coenzyme Qin the presence of ascorbic acid or related compound thereof after reducing oxidized coenzyme Qto reduced coenzyme Qusing ascorbic acid or a related compound thereof, operations are simplified and minimized, and thus reduced coenzyme Qof high quality is produced.

[object Object]

The present invention provides a stabilization method, a preservation method and the like method of reduced coenzyme Q, which is useful as functional nutritive foods, specific health foods and the like. Furthermore, the present invention provides a method for efficiently obtaining reduced coenzyme Qof high quality and by a method suitable for a commercial production. It is possible to handle and stably preserve reduced coenzyme Qunder a condition that oxidation by a molecular oxygen is inhibited by contacting reduced coenzyme Qwith an ascorbic acid and citric acid or a related compound thereof, and thus a stabilized composition is obtained. Moreover, reduced coenzyme Qis converted into a crystalline state in such a condition that the formation of oxidized coenzyme Qas a byproduct is minimized by crystallizing reduced coenzyme Qin the presence of ascorbic acid or a related compound thereof, etc., and thus a reduced coenzyme Qcrystal of high quality is produced. Furthermore, by successively crystallizing the generated reduced coenzyme Q, in the presence of ascorbic acid or related compound thereof after reducing oxidized coenzyme Qto reduced coenzyme Qusing ascorbic acid or a related compound thereof, operations are simplified and minimized, and thus reduced coenzyme Qof high quality is produced.

Method of stabilizing reduced coenzyme q10

The present invention relates to a method for stabilizing reduced coenzyme Q, which is useful as an ingredient in good foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, animal drugs, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc., and to a composition therefor. The composition comprises reduced coenzyme Q, a fat and oil (excluding olive oil) and/or a polyol, and doesn't substantially inhibit the stabilization of reduced coenzyme Q. Additionally, the composition is a reduced coenzyme Q-containing composition which comprises reduced coenzyme Q, a polyglycerol fatty acid ester, and a fat and oil and/or a polyol.

The present invention has its object to provide a method for stably preserving a capsule containing reduced coenzyme Q, which is useful as foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, animal drugs, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc. The present invention relates to a method for preserving reduced coenzyme Qwhich comprises producing or obtaining a capsule containing reduced coenzyme Q, and controlling environment surrounding the capsule to a relative humidity of not less than 0% but not more than 60%. According to this method, reduced coenzyme Qcan be preserved stably, without requiring huge cost and labor, or special equipment.

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Takasago, Japan

Tadao Ono