Chugai Seiyaku Kabushiki Kaisha

Fujirebio Kabushiki Kaisha

Tadao Aoki

Yoshihei Hirasawa

Hideo Miyakoshi

Kunio Konno

Tatsuo Suda

Yasuo Nishii

Etsuko Abe

Mikio Mizukoshi

Sachio Takahashi

A diagnostic method for immune disorders comprising determining the immunoglobulin production or the DNA (deoxyribonucleic acid) synthesis of peripheral blood lymphocytes by stimulation with a new mitogen derived from either disintegrated microorganisms or culture fluid of microorganisms belonging to Staphylococcus.

Diagnostic method for immune disorders

A method of leukemia or leukemoid disease treatment by administration of a vitamin D derivative with a hydroxyl group at 1.alpha.-position is disclosed. It is believed that the vitamin D derivative with a hydroxyl group at 1.alpha.-position is capable of treating cancer through redifferentiation of cancer cells and that this capability is inherent in vitamin D derivatives with a hydroxyl group at 1.alpha.-position.

Method of treating leukemia or leukemoid diseases

A method for inhibiting the lowering of immunological function of patients who are suffering from serious renal disorder such as chronic renal failure or uremia which comprises administering 1.alpha.-hydroxycholecalciferol to the patients is disclosed. An agent useful in the practice of the method is also disclosed.

Method for inhibiting the lowering of immunological function and agent

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Niigata, Japan

Tadao Aoki