Kureha Kagaku Kogyo Kabushiki Kaisha

Tadaaki Kato

Chikao Yoshikumi

Yuji Maeda

Hideyuki Yamato

Takayoshi Fujii

Kenichi Saito

Yasuhiko Kobayashi

Masanori Ikuzawa

Fumisato Yoshino

Kyoya Takahata

Toru Hirai

Teruo Sakagami

Naohiro Murayama

Fumio Hirose

Masayuki Funabashi

Takuji Hosoi

Noriyuki Toyoda

Tsutomu Konno

Yukuo Katayama

Kazuaki Matsui

Sinji Nakajima

Eiji Inoguchi

Junichi Kosugi

Masanori Togawa

Mikio Matsuki

Disclosed herein is a method for preventing senescence and increasing bone mass namely, bone volume and bone strength which method comprises administering 24,25-dihydroxy cholecalciferol in a pharmaceutically effective amount, and also use of 24,25-dihydroxy cholecalciferol for preparing anti-senescent compositions and compositions for increasing bone mass.

Method for preventing senescence and increasing bone mass

Disclosed herein is a method for inhibiting the formation of urinary calculus by the administration of 24,25-dihydroxycholecarciferol.

Method for inhibiting the formation of urinary calculus utilizing

Disclosed herein is a pharmaceutical composition in dosage unit form, which comprises a dosage effective for treating nephritic disease of a compound of 24,25-dihydroxycholecalciferol as an active ingredient and a pharmaceutically acceptable carrier.

Antinephritic pharmaceutical composition containing 24,

Disclosed herein is a pharmaceutical composition in dosage unit form, which comprises a dosage effective for treating osteoporosis of a compound of 24,25-dihydroxycholecalciferol and a pharmaceutically acceptable carrier.

Antiosteoporotic pharmaceutical composition containing

Disclosed is a pharmaceutical composition in dosage unit form which comprises a dosage effective for the treatment of pains and pyrexia, hypertension, hypotension, hyperlipemia, inflammatory diseases or diseases due to the functional accentuation of thrombocytes of a compound of 24,25-dihydroxycholecalciferol and a pharmaceutical acceptable carrier or diluent therefor.

Pharmaceutical composition containing 24,25-dihydroxycholecalciferol in

Disclosed is a pharmaceutical composition in dosage unit form which comprises a dosage effective for the treatment of myodystrophia of a compound of 24,25-dihydroxycholecalciferol and a pharmaceutical acceptable carrier or diluent therefor.

Pharmaceutical composition containing 24,25-dihydroxycholecalciferol as

Pharmaceutical composition in dosage unit form, comprising a therapeutically effective amount of 24,25-dihydroxycholecalciferol and a pharmaceutically acceptable carrier. The compound of 24,25-dihydroxycholecalciferol has anti-hypercalcemic activity, anti-ulcer activity, activity of preventing reduction of immunity, activity of controlling magnesium-metabolism, anti-hyperphosphatemic activity, activity of controlling blood sugar level and anti-tumor activity.

Method for administering 24,25-dihydroxycholecalciferol to persons

Disclosed herein are collagen fibers for use in medical treatments, having amino acid residues of 312 to 340 glycine residues, 119 to 138 proline residues, 94 to 100 hydroxyproline residues and 2.6 to 5.5 tyrosin residues per 1000 total amino acid residues thereof, a denaturation temperature in a range of 31.degree. to 40.degree. C., and S-constant of 1.12 to 1.62.

Collagen fibers for use in medical treatments

A composite material of de-N-acetylated chitin and fibrous collagen, which may be prepared by bringing the de-N-acetylated chitin and the fibrous collagen into mutual contact in an aqueous acidic medium followed by deacidifying the obtained product, the fibrous collagen being able to be partially replaced by gelatin and/or soluble collagen, and a shaped material derived from the composite material is excellent in mechanical strength, heat-resistance and biostability and advantageously employed in the field of medical materials, edibles such as edible casing and base materials for inmobilizing enzyme.

Composite material of de-N-acetylated chitin and fibrous collagen

A method for electrodepositing a protein by electrophoresis onto an ion-exchange membrane from a liquid in which the protein is dissolved or is dispersed in suspension, and an apparatus for the electrodepositing are disclosed.

Method for electrodepositing a protein onto an ion-exchange membrane

A method for preparation of collagen filaments for use in medical treatments comprising the steps of dispersing a finely shredded insoluble collagen material from which impurities have already been removed in an aqueous acidic solution and of subjecting the thus dispersed collagen material to irradiation of ultrasonic waves.

Method for preparing collagen filaments for use in medical treatments

A process for producing a low sulfur content fuel oil in a high yield from a starting oil having a high sulfur content, which comprises (1) treating a residual petroleum oil with hydrogen at a temperature of about 350.degree. to 450.degree. C and a pressure of about 50 to 200 Kg/cm.sup.2 at a liquid hourly space velocity of about 0.2 to 4 l/H.l in the presence of a catalyst, (2) introducing an inert gas or steam at a temperature of about 400.degree. to 900.degree.C and pyrolyzing the treated oil at a temperature of about 350.degree. to 500.degree.C and at a pressure of about atmospheric pressure to 100 Kg/cm.sup.2 with a residence time of about 0.5 to 10 hours, and (3) hydrodesulfurizing the pyrolyzed oil at a temperature of about 300.degree. to 400.degree.C and a pressure of about 30 to 100 Kg/cm.sup.2 at a liquid hourly space velocity of about 0.5 to 4 l/H.l in the presence of a desulfurizing catalyst.

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Tokyo, Japan

Tadaaki Kato