Otsuka Pharmaceutical Factory, Inc.

Tadaaki Inoue

Keiichi Kawakami

Hideshi Okamoto

Koichi Takeda

Yuki Manabe

An object of the present invention is to provide a plastic ampule capable of suppressing volatilization and scattering of a drug solution and elution of plastic compounding ingredients into the drug solution, as well as suppressing whisker formation and deformation and damage of an opening when the plastic ampule is opened. A plastic ampuleaccording to the present invention includes a drug solution storage partfor storing a drug solution, a drug solution discharge tubein communication with the drug solution storage partand extending toward one side, and a top partclosing an end at the one side of the drug solution discharge tube, and the drug solution discharge tubeincludes a fragile partformed to have a thin thickness along a circumferential direction. The drug solution storage part, the drug solution discharge tube, and the top partare formed of a multilayer plastic material that includes an intermediate layer containing a cyclic olefin-based (co)polymer with a glass transition temperature of 60 to 80&#xb0; C., an inner layer laminated to an inner side of the intermediate layer, an outer layer laminated to an outer side of the intermediate layer, and adhesive layers respectively disposed between the intermediate layer and the inner layer and between the outer layer and the intermediate layer.

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Naruto, Japan

Tadaaki Inoue