Hewlett-packard Company

Agilent Technologies, Inc.

Life Technologies Corporation

Pelikan Technologies, Inc.

Peliken Technologies, Inc.

Tad Decatur Simons

Michael Greenstein

Paul K Lum

Dominique M Freeman

David A King

Leslie Anne Leonard

Timothy Updyke

Richard J Pittaro

Paul F Predki

George W Hopkins, Ii

Randall Lowe

Evangeline Gonzalez

Ganapati R Mauze

Hewlett E Melton, Jr

Damien Francis Gray

William F Carlsen, Jr

Frederick A Stawitcke

William M Reed

Paul A Tessier

Edward D Verdonk

Marc J Zeitlin

Jerry Zawadzki

Jeffrey Perry

Timothy Vale Updyke

The present teachings provide methods, devices, systems, and materials for performing electrophoresis in an automated fashion. The electrophoresis system may simultaneously image gel during an electrophoresis run. In some embodiments, the electrophoresis system may analyze an imaged gel during or after electrophoresis. The device may comprise a gel processing system, a gel illumination system, an image capture system, and an image analysis all housed within a housing.

Gel electrophoresis, imaging, and analysis methods, devices, systems, and materials

Electrophoresis apparatus

An apparatus having a shaft that can sense the depth of penetration, for penetrating into an object (the substrate). The substrate being penetrated has impedance that varies according to the depth under a surface of the substrate. The shaft has a tip for penetration and has conductive ends near to the tip of the shaft. A change of impedance of material of the object between the conductive ends can be sensed to provide information on the depth of penetration. A processor can be provided external to the object being penetrated by the shaft to gather and process the impedance information to determine whether the desired depth has been achieved.

Apparatus and method for penetration with shaft having a sensor for sensing penetration depth

A cassette containing cartridges for sampling blood from a patient. The cassette includes a container for storing a plurality of cartridges and at least one cartridge in the container. The cartridge includes a cartridge case and a lancet. The lancet has a tip and is housed in the cartridge case. The lancet can be driven to extend the tip outside the cartridge case for lancing the skin of the patient to yield blood. The container has a compartment that contains at least one cartridge. A cartridge from the compartment can be loaded onto a glucometer that drives the lancet in the cartridge to lance the skin of a patient.

Cassette of lancet cartridges for sampling blood

Method of using cassette of lancet cartridges for sampling blood

An apparatus and method for minimizing a subject's pain perception during an invasive medical procedure, such as blood sampling and the like. The apparatus can include a receiving surface constructed to contact a portion of the subject's skin and a vibratory mechanism associated with the receiving surface such that the vibratory mechanism transmits vibrations through the receiving surface and to the subject's skin. An invasive sharp can be substantially permanently supported and moveably disposed with respect to the receiving surface such that the invasive sharp reciprocates between a first position in which the sharp is spaced from the receiving surface, away from the subject's skin, and a second position in which at least a portion of the sharp protrudes through an opening in the receiving surface.

Apparatus and method for minimizing pain perception

A handheld medical calculator and reference device having an input keypad and an output screen connected to a processor with memory to perform specific clinical functions. The clinical functions include: basic mathematical operations and common scientific functions for routine calculations; store/recall functions for numbers and for routinely used program settings; phone directory; user selection of display modes (fixed, scientific, choice of radix), degree/radian; time, date, and day of week features for timing and alarms (with display format choices); drug and infusion calculations; hemodynamic and cardiac functions; respiratory and pulmonary functions; acid-base functions; nutritional functions; nomograms, maps, and a reference table of normal values; and patient vital signs record keeping.

Handheld medical calculator and medical reference device

A cartridge for sampling and analyzing blood from the skin of a patient. The cartridge has a cartridge case, a lancet, and associated with the cartridge case an analytical region for analyzing the property of blood. The lancet has a tip for lancing the skin and is housed in the cartridge case. The lancet is operatively connected to the cartridge case such that the lancet can be pushed to extend its tip outside the cartridge case for lancing the skin to yield blood. The blood from the lancing wound is transferred to the analytical region and be analyzed.

Lancet cartridge for sampling blood

A blood sampling apparatus for sampling blood from the skin of a patient for analysis. The apparatus includes a cartridge and a housing with a driver. The cartridge has a cartridge case, lancet, and a compartment associated with the cartridge case for receiving blood. The lancet is housed in the cartridge case and operatively connected thereto such that it is drivable to extend outside the cartridge case through a lancing opening for lancing the skin to yield blood. The housing has a driver for urging the lancet to extend outside the cartridge case. During lancing, the cartridge is preferably detachably held in the housing such that the cartridge can be disassociated from the driver after sampling blood.

Integrated system and method for sampling blood and analysis

A blood sampling device for penetrating skin to obtain a blood sample is disclosed. The blood sampling device has a blade structure that can be extended from a housing to pierce the skin and then retracted. The blade structure has at least two blades each including a cutting edge. The blades abut one another to form a rigid joint from which the blades extend. The blades each have a distal portion in which the distance from the rigid joint to the cutting edge decreases towards and terminates at a sharp point at a distal end. Each blade generally forms an angle less than 180 degrees with at least one neighboring blade. This structure decreases the tendency of the blade structure to flex as the distal end of the blade structure penetrates the skin to yield blood.

Apparatus and method for minimally invasive blood sampling

A blood analysis apparatus for obtaining blood for analysis from the skin of a patient with a controlled degree of lancing. The apparatus including a cartridge and a driver. The cartridge includes a cartridge case and a lancet. The lancet has a tip and is housed in the cartridge case. The lancet can be driven to extend the tip outside the cartridge case through an opening for lancing the skin of the patient to yield blood. The driver drives the lancet to move the tip distally to lance the skin. The driver is triggerable by the skin which is to be lanced exerting a force exceeding a preset amount against the triggering mechanism of the apparatus, to drive the lancet toward the skin.

Reproducible lancing for sampling blood

A gas analysis apparatus for analysis of sample gas wherein the apparatus has a mechanism for cleaning optical elements such as reflectors and windows in the apparatus is provided. The gas analysis apparatus includes a light source for emitting light, a body having an isolated cavity in which the light emitted by the light source propagates, a detector for analyzing light scattered by the sample gas in the isolated cavity, and a spraying system connected to the body to spray a sublimable substance. The isolated cavity has one or more optical elements each with a surface. The spray of the sublimable substance is directed onto such a surface for in situ removal of contaminants. The body has a sample inlet port for introducing the sample gas into the cavity and an outlet port for venting gas from the cavity.

Gas analyzer with arrangement for spray-cleaning optical element

Growing community of inventors

Palo Alto, CA, United States of America

Tad Decatur Simons