Nereus Pharmaceuticals, Inc.

University of California

Other

Ta-Hsiang Chao

Barbara Christine Potts

Venkat Rami Reddy Macherla

Katherine A McArthur

Rama Manam

Saskia Theodora Cornelia Neuteboom

Kin S Lam

Michael A Palladino

Emmanuel A Theodorakis

Benjamin Nicholson

Scott Sherman Mitchell

Venkat Macherla

Ram Rao Manam

Saskia Neuteboom

Cheryl L Billstrom

Katherine Anne Reed

Young Ger Suh

Young-Ger Suh

Disclosed herein are compounds of Formula (I) that include a sulfonate ester, ester or ether group. Compounds of Formula (I) can be included in pharmaceutical compositions, and can be used to treating and/or ameliorating a disease or condition, such as cancer, a microbial disease and/or inflammation.

Proteasome inhibitors

Described herein are chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. Also described are methods of synthesizing natural products and novel, structurally-related chemical compounds. More particularly, disclosed are new analogs of and processes for the preparation of compounds and pharmaceutical compositions thereof useful in the treatment of, for example, inflammation, cancer, multiple myeloma, cachexia, cardiovascular disease, anti-infectious, diabetes, otitis media, sinusitis and transplant rejection.

Interleukin-1 and tumor necrosis factor-&#x3b1; modulators; syntheses of such modulators and methods of using such modulators

Interleukin-1 and tumor necrosis factor-&#x3b1;modulators; syntheses of such modulators and methods of using such modulators

Compounds of Formulae I-VI and derivatives thereof having anti-cancer, anti-inflammatory, and anti-microbial properties and to compositions that include one or more of compounds and their derivatives or analogs having anti-cancer, anti-inflammatory and anti-microbial properties are disclosed. Pharmaceutical compositions comprising such compounds and methods of treating cancer, inflammatory conditions, and microbial infections with the disclosed compounds or the disclosed pharmaceutical compositions are also disclosed.

[3.2.0] Heterocyclic compounds and methods of using the same

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San Diego, CA, United States of America

Ta-Hsiang Chao