Precisense A/s

Novo Nordisk A/s

Medtronic Minimed, Inc.

Covidien LP

Søren Aasmul

Thomas Buch-Rasmussen

Philip E Hansen

James M Flink

Claus Juul Mortensen

Jens Ulrich Poulsen

Jacob D Dove

Jesper Svenning Kristensen

David J Miller

Henning Munk Ejlersen

William S Smith

An example device includes processing circuitry configured to receive, from an oxygen sensor, an ambient air signal indicative of an oxygen partial pressure of ambient air. The processing circuitry is further configured to receive, from an atmospheric pressure sensor, an atmospheric pressure sensor signal indicative of atmospheric pressure. The processing circuitry is configured to determine, based on the atmospheric pressure sensor signal, an oxygen partial pressure of the ambient air, determine, based at least in part on the oxygen partial pressure of the ambient air and the ambient air signal, the one or more calibration parameters, and calibrate, based on the one or more calibration parameters, the oxygen sensor. The calibrated oxygen sensor may be used to, for example, determine the oxygen content of urine of a patient to monitor renal function of the patient.

Oxygen sensor calibration

An injection apparatus for making an injection at a predetermined depth in skin comprises: a skin positioning member, an injection needle (), and means guiding the injection needle for movement from a parking position above the skin beside said skin positioning member to slide beneath said skin positioning member to an injection position; wherein: the tip () of the injection needle is closer to the longitudinal axis of the shaft portion () than is the outside of the shaft portion () and/or the length of the lumen opening () of the needle is in a range from 5 to 15 times the diameter of the shaft () of the needle. An injection needle wherein the length of the lumen opening () of the needle is in a range from 5 to 15 times the diameter of the shaft () of the needle.

Injection apparatus and special needle for making an injection at a predetermined depth in the skin

Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.

Dry mouldable drug formulation

An injection apparatus for making an injection at a predetermined depth in skin comprises: a first skin positioning member, a second skin positioning member, wherein the first and second skin positioning members lie or are moveable to lie in an injection arrangement; an injection needle; and an injection needle movement guide to guide the injection needle for movement from a parking position above the skin, through the lower surface of the second skin positioning member to slide beneath the first skin positioning member to an injection position. A further injection apparatus comprises: an injection needle; a plunger within the injection needle; and a retractor to retract the injection needle such that material to be injected is expelled from the injection needle by the plunger.

Injection apparatus

In apparatus for the production and detection of fluorescence at a sample surface, the height of the apparatus above the sample surface is reduced, and loss of the emitted fluorescence due to reflection loss and light scattering is minimized. The apparatus comprises a three-dimensionally curved light reflecting surface () that directs light from a light source () transversely to its original path and focuses the light on to an illumination zone () at or below the sample surface. The reflecting surface () also collects, directs and at least partially collimates emitted fluorescence transversely to its original path and towards a detector ().

Fluorometers

Solid pharmaceutical compositions and methods of making and administering for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.

A first light source emits a light signal along a measurement optical path that includes a sample and a second light source emits a light signal along a dummy measurement optical path. A measurement circuit receives the light signals and provides outputs separated in time which are indicative of the phase of the respective light signals. A phase shift is induced in light in the measurement optical path by the sample. A reference circuit receives a signal indicative of the phase of the light signals emitted by the first and second light sources. Circuitry compares the phases of light output from the two circuits to provide output indicative of a first measured phase difference during operation of the first light source. Correction is applied to this measurement by taking a similar phase difference measurement during operation of the second light source and comparing the two phase differences.

Growing community of inventors

Holte, Denmark

Søren Aasmul