Sanwa Kagaku Kenkyusho Co., Ltd.

Syoji Yokochi

Masayasu Kurono

Kiichi Sawai

Takahiko Mitani

Yoshiro Ishiwata

Kyoichi Asano

Yasuaki Kondo

Ryoichi Unno

Takuji Kakigami

Naohisa Ninomiya

Makoto Sato

Yutaka Baba

Hiromoto Kimura

Masato Fukushima

Toshiyuki Kouzaki

Noriyuki Iwata

Kaneo Yamada

Hiroyuki Ohwaki

Takashi Meguro

Masashi Taki

Takao Matumoto

Yuichi Shiokawa

Kougaku Isogawa

Tamaki Ohtuka

Mikio Minamitani

The invention provides a novel glycoside which contains as the aglycon a 4-(substituted phenyl)piperazine-1-yl derivative of glycyrrhetinic acid and 11-deoxo-glycyrrhetinic acid or their derivative as well as a composition for the treatment of virus infection, which contains these compounds as a main active component.

Glycyrrhetinic acid derivatives

A 3-oxygermylpropionic acid preparation is provided, which activates the action of 3-oxygermylpropionic acid having the general formula: [(O.sub.1/2).sub.3 GeCH.sub.2 CH.sub.2 COOH]n wherein n=an integer of at least 1 and is readily solubilized and disintegrated in vivo. The present preparation is manufactured by compression-molding at high pressure a composition comprising 3-oxygermylpropionic acid and two or more low-molecular substance of high solubility in water. The low-molecular substances are selected from the group consisting of white sugar, sorbitol, fructose, sucrose, glucose, lactose, mannitol and sodium chloride.

Binder-free orally administrable tablet containing 3-oxygermylpropionic

An organic germanium compound to be effectively used for curing AIDS or making AIDS asymtomatic in various forms is expressed by the following rational formula: ##STR1## wherein n is an integer of 1 or 2 or more, is in the form of a white acicular or needle crystal, shows a solubility of 1.570/100 ml in water at 25.degree. C. and exhibits a melting (decomposition) point of 240.degree. C.

Composition for enhancing biosynthesis of interferon

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Nagoya, Japan

Syoji Yokochi