Other

Institut National De La Sante Et De La Recherche Medicale

Meristern Therapeutics

Sylvie Baudino

Bertrand Merot

Philippe Lenee

Veronique Gruber

Michael Marden

Claude Poyart

Wilfrid Dieryck

Renee-Josee Pagnier

Claude Benicourt

V&eacute;ronique Gruber

Claire Cudrey

A method for producing haemin proteins by (i) inserting into plant cells one or more nucleic acid molecules that each comprise at least one sequence coding for a protein component of an animal haemin protein capable of reversibly binding oxygen, or for a variant or portion of said protein component, and optionally a sequence coding for a selection agent; (ii) selecting cells containing nucleic acid coding for the protein component of the haemin protein; (iii) optionally propagating the transformed cells either in a culture or by regenerating whole transgenic or chimeric plants; and (iv) recovering and optionally purifying a haemin protein that includes a complex consisting of the protein or proteins coded for by said nucleic acid and at least one iron-containing porphyritic nucleus, or a plurality of such complexes.

Method for producing hemin proteins using plant cells, resulting proteins and products containing same

Recombinant preduodenal lipases and polypeptides derivatives produced by plants, processes for obtaining them and their uses

A method for producing human hemoglobin proteins by (i) inserting into plant cells one or more nucleic acid molecules that each comprise at least one sequence coding for a protein component of a human hemoglobin protein capable of reversibly binding oxygen, and optionally a sequence coding for a selection agent; (ii) selecting cells containing nucleic acid coding for the protein component of the human hemoglobin protein; (iii) optionally propagating the transformed cells either in a culture or by regenerating whole transgenic or chimeric plants; and (iv) recovering and optionally purifying the human hemoglobin protein that includes a complex consisting of the protein or proteins coded for by the nucleic acid and at least one iron-containing polphyritic nucleus, or a plurality of such complexes.

Method for producing human hemoglobin proteins using plant cells

Growing community of inventors

Orcines, France

Sylvie Baudino