Alza Corporation

Sylvia L Seroff

Atul D Ayer

David E Edgren

Andrew C Lam

Michael A DesJardin

Noymi Yam

Padmanabh Bhatt

Phillip R Nixon

Noymi V Yam

Dosage forms and methods for providing sustained release of reboxetine are provided. The sustained release dosage forms provide therapeutically effective average steady-state plasma reboxetine concentrations when administered once per day. This once-a-day dosing regimen results in only one peak plasma reboxetine concentration occurrence in each 24 hour period. In addition, the peak plasma reboxetine concentration occurs at a later time following dose administration and exhibits a lesser magnitude than the peak plasma reboxetine concentration that occurs following administration of reboxetine in an immediate-release dosage form.

Methods for providing effective reboxetine therapy with once-a-day dosing

Dosage forms and methods for providing effective reboxetine therapy with once-a-day dosing

Growing community of inventors

Sunnyvale, CA, United States of America

Sylvia L Seroff