Centre National De La Recherche Scientifique

Arkema France

Université´ D'aix-Marseille

Universitë De Bordeaux

Total Petrochemicals France

Sylvain Marque

Denis Bertin

Olivier Guerret

Jean-Luc Couturier

Paul Tordo

Didier Gigmes

Bruno Vuillemin

Michel Duc

Gérard Audran

Jean-Michel Franconi

Florence Chauvin

Pierre-emmanuel Dufils

Paul Bremond

Philippe Mellet

Damien Moncelet

Christophe Galindo

Pierre Voisin

Pierre-Emmanuel Dufils

The present invention relates to alkoxyamines of general formula (I), and to compounds of general formula (IIa), (IIb), (IIc), (IId), IIe), (IIf) or (IIg), as such and for the treatment of cancers. 

Alkoxyamines for the treatment of cancers

The present invention relates to a process for preparing a high impact monovinylaromatic polymer comprising admixing a rubber, at least one monovinylaromatic monomer and optionally one or more comonomer in the presence of at least a borane complex of the L-BHtype wherein L is a Lewis base and polymerizing the monovinylaromatic monomer. The borane complex initiator, L may be an ether (e.g THF, tetrahydrofurane), a thioether (e.g dimethylthioether) or an amine. A preferred complex is an amine borane such as by way of example triethylamine borane. The present invention also relates to a high impact monovinylaromatic polymer having a weight ratio of grafted monovinylaromatic monomer and optional comonomer to the initial monovinylaromatic monomer and optional comonomer above 0.1%, advantageously above 2% and preferably in the range 2 to 4%. The invention is of particular interest to make high impact polystyrene.

Process for preparing high impact monovinylaromatic polymers in the presence of a borane complex

A subject-matter of the invention is alkoxyamines resulting from &#x3b2;-phosphorated nitroxides corresponding to the formula: in which R represents an alkyl radical having a number of carbon atoms ranging from 1 to 3, Rrepresents a hydrogen atom or a residue: in which Rrepresents an alkyl radical having a number of carbon atoms ranging from 1 to 20, and Rrepresents a hydrogen atom, an alkyl radical having a number of carbon atoms ranging from 1 to 8, a phenyl radical, an alkali metal, such as Li, Na or K, HN, BuNor BuHN, exhibiting a kinetic dissociation constant kd, measured at 120&#xb0; C. by EPR, of greater than 0.05 s. These compounds can be used as initiators for the (co)polymerizations of at least one monomer which can be polymerized by the radical route.

Alkoxyamines originating from &#x3b2;-phoshorated nitroxides and use thereof in radical polymerisation

The invention relates to the use of alkoxyamines of formula (I): for the preparation of polymerized or non-polymerized mono- or polyalkoxyamines of formula (II): 

Alkoxyamines derived from beta-phosphorylated nitroxides, and use thereof for preparing polymerized or non-polymerized mono- or polyalkoxyamines

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Antraigues sur Volane, France

Sylvain Marque