Tata Consultancy Services Limited

Swati Jindal

Gaurav Gupta

Lovekesh Vig

Monika Sharma

Method and system for automatic chromosome classification is disclosed. The system, alternatively referred as a Residual Convolutional Recurrent Attention Neural Network (Res-CRANN), utilizes property of band sequence of chromosome bands for chromosome classification. The Res-CRANN is end-to-end trainable system, in which a sequence of feature vectors are extracted from the feature maps produced by convolutional layers of a Residual neural networks (ResNet), wherein the feature vectors correspond to visual features representing chromosome bands in an chromosome image. The sequence feature vectors are fed into Recurrent Neural Networks (RNN) augmented with an attention mechanism. The RNN learns the sequence of feature vectors and the attention module concentrates on a plurality of Regions-of-interest (ROIs) of the sequence of feature vectors, wherein the ROIs are specific to a class label of chromosomes. The Res-CRANN provides higher classification accuracy as compared to the state-of the-art methods for chromosome classification.

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Gurgaon, India

Swati Jindal