Codexis, Inc.

Svetlana Balatskaya

Fernando Valle

Jonathan Vroom

Louis Clark

Kristian Karlshoej

Kaman Chan

Yoram Barak

Emily Mundorff

Ish Kumar Dhawan

Richard John Fox

Matthew B Tobin

Birthe Borup

Catherine M Cho

Ranjini Chatterjee

Kenneth W Mitchell

Patricia Choudhary

Trish Choudhary

Les Partridge

Recombinant microorganisms are provided which have been engineered to produce fatty alcohols. Also provided are recombinant microorganisms which comprise a heterologous polynucleotide encoding a fatty alcohol reductase enzyme and an introduced polynucleotide encoding a &#x3b2;-ketoacyl acyl carrier protein synthase.

Production of fatty alcohols from engineered microorganisms

Recombinant bacterial microorganisms are provided which comprise heterologous fatty acyl reductases ('FAR') polypeptides wherein said microorganisms have been engineered to produce increased amounts of saturated fatty alcohols and methods of making saturated fatty alcohols using the recombinant bacterial microorganisms.

Production of saturated fatty alcohols from engineered microorganisms

The present disclosure relates generally to polypeptides having improved alanine 2,3-aminomutase (AAM) activity, the polynucleotides encoding the AAM polypeptides, and expression vectors and host cells for expressing the AAM polypeptides.

Alanine 2,3-aminomutases and related polynucleotides

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Fremont, CA, United States of America

Svetlana Balatskaya