Koninklijke Philips Corporation N.v.

University of California

Sven Prevrhal

Michael Grass

Joerg Bredno

Holger Schmitt

Eberhard Sebastian Hansis

Hannes Nickisch

David Sowards-Emmerd

Liran Goshen

Lingxiong Shao

Heinrich Schulz

Steffen Renisch

Thomas Blaffert

Nicole Schadewaldt

Mordechay Pinchas Freiman

Thomas Koehler

Shyam Bharat

Jochen Kruecker

Balasundar Iyyavu Raju

Jinghan Ye

Craig Steven Levin

Christian Haase

Xiyun Song

Chi-Hua Tung

Jörg Sabczynski

Jingyu Cui

Neriman Nicoletta Kahya

Andreas Goedicke

Andriy Yaroshenko

Claudia Errico

Yechiel Lamash

Patrick Olivier

Marco Verstege

Guillem Pratx

Amy Perkins

Manindranath Vembar

Roberto Buizza

Jason Stephen Wiener

Benjamin M Yeh

Jean Rinkel

Carlos Forsythe

Eberhard Sevastian Hansis

Seyedali Sadeghi

Samer Bou Jawde

A lung injury monitoring system () configured to monitor a patient's lungs during ventilation, comprising: an ultrasound device () configured to obtain an ultrasound image of the patient's lungs during ventilation of the patient; a processor () configured to: (i) receive the obtained ultrasound image; (ii) determine a ventilation phase of the ventilator; (iii) analyze the received ultrasound image; and (iv) determine a risk score for a potential ventilator-associated lung injury (VALI); and a user interface () configured to display the determined risk score for the potential VALI.

Methods and systems for ventilation management using lung ultrasound

The invention refers to an apparatus that allows to improve the image quality of nuclear images, e.g. PET images. The apparatus () comprises a providing unit () for providing nuclear image data of a region of interest, a providing unit () for providing a motion signal indicative of a motion of the region of interest, a determination unit () for determining different motion states of the region of interest based on the motion signal, a determination unit () for determining for each motion state nuclear image data corresponding to the motion state, a reconstruction unit () for reconstructing an absorption map for each motion state based on the corresponding nuclear image data of the respective motion state, and a reconstruction unit () for reconstructing one or more nuclear images of the region of interest based on the nuclear image data and the absorption maps reconstructed for each motion state.

Apparatus, system, method and computer program for providing a nuclear image of a region of interest of a patient

A computing system () includes a computer readable storage medium () with computer executable instructions (), including: a biophysical simulator () configured to simulate coronary or carotid flow and pressure effects induced by a cardiac valve device implantation, using cardiac image data and a device model (). The computing system further includes a processor () configured to execute the biophysical simulator to simulate the coronary or carotid flow and the pressure effects induced by the device implantation with the cardiac image data and the device model. The computing system further includes a display configured to display results of the simulation.

Simulation of transcatheter aortic valve implantation (TAVI) induced effects on coronary flow and pressure

Augmented reality (AR) servicing guidance uses a mobile device () with a display and a camera. Computer vision (CV) processing () such as Simultaneous Location and Mapping (SLAM) is performed to align AR content () with a live video feed () captured by the camera. The aligned AR content is displayed on the display of the mobile device. In one example, the mobile device is a head-up display (HUD) () with a transparent display () and camera (). In another example the mobile device is a cellphone or tablet computer () with a front display () and a rear-facing camera (). The AR content () is generated by CV processing () to align () AR content with recorded video () of a service call. The aligning () includes aligning locations of interest (LOIs) identified in the recorded video of the service call by a user input.

Self-expanding augmented reality-based service instructions library

A computing system () includes a computer readable storage medium () with computer executable instructions (), including a biophysical simulator () and an electrocardiogram signal analyzer (). The computing system further includes a processor () configured to execute the electrocardiogram signal analyzer determine myocardial infarction characteristics from an input electrocardiogram and to execute the biophysical simulator to simulate a fractional flow reserve or an instant wave-free ratio index from input cardiac image data and the determined myocardial infarction characteristics.

Coronary artery disease metric based on estimation of myocardial microvascular resistance from ECG signal

The invention relates to a system and a method for active grating position tracking in X-ray differential phase contrast imaging and dark-field imaging. The alignment of at least one grating positioned in an X-ray imaging device is measured by illuminating a reflection area located on the grating with a light beam, and detecting a reflection pattern of the light beam reflected by the reflection area. The reflection pattern is compared with a reference pattern corresponding to an alignment optimized for X-ray differential phase contrast imaging, and the X-ray imaging device is controlled upon the comparison of the reflection pattern and the reference pattern.

Active gratings position tracking in gratings-based phase-contrast and dark-field imaging

The invention relates to a navigation system for navigating an interventional device () like a catheter and an interventional system comprising the navigation system. A position and shape determining unit () determines and stores a first position and shape of the interventional device within a living being () during a first interventional procedure like a first chemoembolization session and determines a second position and shape of an interventional device within the living being during a subsequent second interventional procedure like a second chemoembolization session. During the second interventional procedure the interventional device is navigated based on the stored first position and shape and based on the second position and shape. This allows considering during the second interventional procedure the path of the interventional device used during the first interventional procedure. In particular, this allows navigating the interventional device along the same path during the first and second interventional procedures.

Navigation system

An imaging system () includes a data acquisition system () configured to produce projection data and at least one memory device with reconstruction algorithms () and at least one blending algorithm (524). The imaging system further includes a reconstructor () configured to reconstruct the projection data with the reconstruction algorithms and generate at least first spectral volumetric image data corresponding to a first basis material content and second spectral volumetric image data corresponding to a second basis material content, and blend the first spectral volumetric image data and the second spectral volumetric image data with the at least one blending algorithm to produce blended volumetric image data.

Material-selective adaptive blending of volumeiric image data

The present disclosure relates to a method for controlling a magnetic resonance imaging guided radiation therapy apparatus comprising a magnetic resonance imaging system. The method comprises: acquiring magnetic resonance data using the magnetic resonance imaging system and the pulse sequence from an imaging volume; segmenting the magnetic resonance data into a plurality of segments indicating respective tissues in the imaging volume; creating a bulk electron density map of the imaging volume from the plurality of segments; displaying the bulk electron density map and radiation dose distributions for the plurality of segments on a graphical user interface, wherein the radiation dose distributions are determined using the bulk electron density map; receiving a modification signal for modifying at least a first segment of the segments; recreating the bulk electron density map using the modified first segment, and recalculating the radiation dose distribution using the bulk electron density map; redisplaying the bulk electron density map and the radiation dose distributions on the graphical user interface.

Radiotherapy planning with improve accuracy

A computing system () includes a computer readable storage medium () with computer executable instructions (), including: a segmentation standardizer () configured to determine a standardized vascular tree from a segmented vascular tree segmented of volumetric image data and a predetermined set of pruning rules (), and a biophysical simulator () configured to perform a biophysical simulation based on the standardized vascular tree. The computing system further includes a processor () configured to execute the segmentation standardizer to determine the standardized vascular tree from the segmented vascular tree segmented of volumetric image data and the predetermined set of pruning rules, and configured to execute the biophysical simulator to perform a biophysical simulation based on the standardized vascular tree. The computing system further includes a display configured to display at least one of the standardized vascular tree and a result of the biophysical simulation.

Vascular tree standardization for biophysical simulation and/or an extension simulation for pruned portions

Stenosis information is obtained by obtaining photographic image data () from a displayed image of a blood vessel () containing the stenosis. Contours of the blood vessel and the stenosis are detected and dimensions are estimated from the photographic image data. A blood vessel model is reconstructed and fractional flow reserve data is calculated using the blood vessel model.

Mobile FFR simulation

The present invention teaches a method and system for computing an alternative electron density map of an examination volume. The processing system is configured to compute a first electron density map using a plurality of imaging data, compute a second electron density map, wherein the second electron density map is a simplified version of the first electron density map, and compute the alternative electron density map, using the first electron density map and the second electron density map.

Fall-back solution for uncertain regions in MRCAT images

The invention relates to an apparatus for determining a fractional flow reserve (FFR) value of the coronary artery system of a living being (). A fractional flow reserve value determination unit () determines the FFR value by using an FFR value determination algorithm that is adapted to determine the FFR value based on a boundary condition and a provided representation of the coronary artery system, wherein the boundary condition is specific for the living being and determined by a boundary condition determination unit (). Since the boundary condition determination unit determines a boundary condition, which is specific for the living being, and since the fractional flow reserve value determination unit not only uses the provided representation of the coronary artery system, but also the living being specific boundary condition for determining the FFR value, the accuracy of the FFR value, which is non-invasively determined, can be improved.

Apparatus for determining a fractional flow reserve value

The present invention relates a segmentation apparatus () for interactively segmenting blood vessels () in angiographic image data (). The segmentation apparatus () comprises a significant location determining unit () for determining one or more locations of a current segmentation () of the blood vessels () in the angiographic image data () as significant locations () at which the current segmentation () has a predetermined influence on a value of a blood flow parameter that is calculated based on the current segmentation (), and a display unit () for displaying the significant locations () to an operator. Thereby, the operator can be guided to focus his/her segmentation efforts to those locations of the current segmentation () that are most relevant for the accuracy of the calculation of the value of the blood flow parameter. This may ease the burden on the operator during the segmentation procedure.

Segmentation apparatus for interactively segmenting blood vessels in angiographic image data

The invention relates to a processing apparatus for processing cardiac data of a living being and to an imaging system comprising the processing apparatus. A distribution of Fractional flow reserve (FFR) values being indicative of the FFR of different coronary arteries of the living being, a distribution of myocardial perfusion values like values of an iodine map being indicative of the myocardial perfusion of different portions of the myocardium of the living being and assignments between coronary arteries and portions of the myocardium of the living being are used for determining degrees of correspondence between FFR values and myocardial perfusion values. This allows for, for example, a determination of the reliability of the FFR values, if the myocardial perfusion values are known to be reliable, based on the determined degrees of correspondence.

Processing apparatus for processing cardiac data

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Hamburg, Germany

Sven Prevrhal