Astra Lakemedel Aktiebolag

Sven O Ogren

Seth O Thorberg

Svante Bertil Ross

Ulf H Lindberg

Gosta L Florvall

Karl S Bengtsson

Zalman Amit

Compounds having antipsychotic activity, characterized by the formula ##STR1## in which formula R.sub.o and R.sub.1 are the same or different and are each selected from hydrogen, halogen, alkyl having 1, 2 or 3 carbon atoms, alkoxy having 1, 2 or 3 carbon atoms, and trifluoromethyl, and R.sub.2 is selected from hydrogen, halogen, alkyl having 1, 2 or 3 carbon atoms, alkoxy having 1, 2 or 3 carbon atoms, and trifluoromethyl, pharmaceutical compositions containing them, and a method for the treatment of psychoses.

Anti-psychotic phthalimidine derivatives

A compound of the formula ##STR1## wherein R.sup.1 is an alkyl group with 1-3 carbon atoms, R.sup.2 and R.sup.3 are the same or different and each is hydrogen, chlorine or bromine; and pharmaceutically acceptable salts and optical isomers thereof; methods and intermediates for the preparation of the compounds; pharmaceutical preparations containing them and their medical use for the treatment of psychoses.

2,6-Dialkoxybenzamides, intermediates, pharamaceutical compositions and

A compound of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof, in which formula the group R.sup.0 is selected from the group consisting of hydrogen, chlorine, bromine, methyl, trifluoromethyl and methoxy. Pharmaceutical compositions containing these compounds are useful for treatment of depressive disorders.

Compounds having antidepressive activity

A method for alleviating alcoholism comprising administering to a host in need of treatment an effective amount of the compound 4-methyl-1-homopiperazinedithiocarboxylic acid or a salt thereof, and a pharmaceutical preparation for alleviation of alcoholism comprising said compound or salt as an active ingredient.

Method of treatment

A compound of the formula ##STR1## and pharmaceutically acceptable acid addition salts thereof, in which formula the group R.sup.o is trifluoromethyl. Pharmaceutical compositions containing these compounds are useful for treatment of depressive disorders.

Trifluoromethyl substituted compounds having antidepressive activity

A compound of the formula ##STR1## and pharmaceutically acceptable acid addition salts thereof, in which formula the group R.sup.o is selected from hydrogen, chlorine, bromine, methyl, trifluoromethyl and methoxy. Pharmaceutical compositions containing these compounds are useful for treatment of depressive disorders.

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Sodertalje, Sweden

Sven O Ogren