Archimica Gmbh

Sven Nerdinger

Andreas Meudt

Victor Snieckus

Claudius Boehm

Bernd Lehnemann

Jörg Jung

Till Vogel

Claudius Böhm

Process for preparing nitriles by reacting N-alkylcarboxamides (RCO&#x2014;NHR) or ammonium salts of carboxylic acids (RCOO&#x2014;NHR) or carboxylic acids in the presence of alkylamines or ammonium salts (RCOOH+NHR, RCOOH+NHR), respectively, R being an arbitrarily substituted linear or branched C-C-alkyl radical, a C-Ccycloalkyl radical or an alkenyl, alkynyl or aryl or heteroaryl radical and Rbeing an arbitrary substituted, linear or branched C-Calkyl radical, a C-Ccycloalkyl radical or an alkenyl or alkynyl radical, with phosphonic anhydrides in the presence of an optional base in an organic solvent at a temperature in the range from &#x2212;30 to 180&#xb0; C. In advantageous embodiments, the phosphonic anhydride is a 2,4,6-substituted 1,3,5,2,4,6-trioxatriphosphinane 2,4,6-trioxide of the formula (I) 

Process for preparing nitriles by elimination reactions

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Kiefersfelden, Germany

Sven Nerdinger