Csl Limited

Euroimmun Medizinische Labordiagnostika Ag

Csl Behring Gmbh

Westfaelische Wilhelms-universitaet Muenster

Julius-maximilians-universitaet Wuerzburg

Westfalische Wilhelms-universität Münster

Sven Meuth

Marc Nolte

Christian Probst

Lars Komorowski

Yvonne Denno

Winfried Stöcker

Ramona Miske

Madeleine Scharf

Brent Steven McKenzie

Inga-Madeleine Dettmann

Christoph Kleinschnitz

Bianca Teegen

Nico Melzer

Heinz Wiendl

Kerstin Goebel

Winfried STÖCKER

Brent Mckenzie

Polypeptides including Neurochondrin and autoantibodies binding to polypeptides including Neurochondrin are provided. Methods for diagnosing or treating diseases associated with neurological symptoms or cancers are also provided. The methods of diagnosis may include detecting an autoantibody binding to Neurochondrin in a sample from a patient. The methods of treatment may include administering a polypeptide comprising Neurochondrin to a patient.

Detection of anti-neurochondrin autoantibody in patients with cerebellar ataxia or cerebellitis

This application relates to neurological inflammatory diseases, such as multiple sclerosis, and to methods of administering a Factor XII inhibitor to prevent, treat, or otherwise ameliorate the effects of a neurological inflammatory disease, such as multiple sclerosis. Agents and pharmaceutical compositions comprising agents which inhibit the activity of FXII are also provided.

Factor XII inhibitors for the treatment of neurological inflammatory disorders

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Muenster, Germany

Sven Meuth