Sofradim Production

Centre National De La Recherche Scientifique

Institut National Polytechnique De Toulouse

Suzelei Montanari

Pierre Bailly

Philippe Gravagna

Michel Therin

Yves Bayon

Alfredo Meneghin

Aurelie Serrero

Mylene Desorme

Pearl Rey

Xavier Bourges

Robert Vestberg

Delphine Petit

Nicolas Prost

Daniel Samain

Sebastien Francois

Mylène Desorme

Jean-Stéphane Condoret

Jean Stephane Condoret

Michel Vignon

Benjamin Renault

Severine Camy

Jean-Stephane Condoret

Aurélie Serrero

Jean Stéphane Condoret

Séverine Camy

A prosthesis includes a piece of biocompatible material having a preformed three-dimensional shape including: a first portion forming a partial spherical cap surface, shaped and dimensioned so as to substantially conform to the shape of the anterior abdominal wall; a second portion extending from an inferior edge of the first portion and forming a wavy-shaped wall, shaped and dimensioned so as to substantially conform to the shape of the psoas muscle; and a corner portion extending from the first portion.

Prosthesis for inguinal hernia repair

The present invention relates to a prosthetic fabric comprising an arrangement of yarns defining at least two faces for said fabric, said fabric comprising, on at least one of its faces, one or more barbs that protrude outwards relative to said face, characterized in that said barbs are covered with a coating made of a water-soluble biocompatible material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.

Fabric with barbs coated with a water-soluble material

The present invention relates to a prosthetic fabric () comprising an arrangement () of yarns that define at least first and second opposite faces () for said fabric, said fabric comprising on at least said first face, one or more barbs () that protrude outwards relative to said first face, said fabric being covered, at least partly, on said second face with a microporous layer made of a bioresorbable material, said barbs being covered with a coating made of a water-soluble material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.

Gripping fabric coated with a bioresorbable impenetrable layer

The present invention relates to methods of repairing an inguinal hernia defect including . . . a first portion forming a partial spherical cap surface shaped and dimensioned . . . a second portion extending from an inferior edge of the first portion . . . characterized in that the piece further includes: a third portion forming an arched part extending longitudinally in the inferior direction from a medial inferior corner of the first portion, the arched part extending radially substantially in the front direction, the third portion being intended to face the medial inferior area of the inguinal anatomy, and introducing the prosthesis into a patient.

The present invention relates to a prosthesis for repairing a inguinal hernia defect. The prosthesis includes a piece of biocompatible material having a preformed three-dimensional shape including: a first portion forming a partial spherical cap surface, shaped and dimensioned so as to substantially conform to the shape of the anterior abdominal wall; a second portion extending from an inferior edge of the first portion and forming a wavy-shaped wall, shaped and dimensioned so as to substantially conform to the shape of the psoas muscle; and a third portion forming an arched part extending longitudinally in the inferior direction from a medial inferior corner of the first portion, the arched part extending radially substantially in the front direction, the third portion being intended to face the medial inferior area of the inguinal anatomy.

The present invention relates to an implant () comprising:

Implant comprising oxidized cellulose and method for preparing such an implant

The present invention relates to an implant () comprising: &#x2014;a substrate () the surface of which comprising oxidized cellulose, said oxidized cellulose having a degree of oxidation ranging from 0.0 to 1, and &#x2014;a multilayer coating covering said substrate, said multilayer coating comprising at least a first layer () adjacent said substrate, said first layer being formed of chitosan, and a second layer () adjacent said first layer, said second layer being formed of oxidized cellulose having a degree of oxidation ranging from 0.5 to 1. The invention further relates to a method for preparing such an implant.

A method for manufacturing an implantable film and a prosthesis comprising such a film The present invention relates to a method for manufacturing a non porous film intended to be implanted in the human body, said method comprising the following steps: preparation of a first film, called intermediate film, via gelling of a starting solution comprising at least one polymer selected in the group consisting of collagen, glycosaminoglycans, and mixtures thereof, immersion of said intermediate film in an alkaline composition comprising at least one C-Calcohol, drying of the film obtained at the end of the immersing step. The invention also relates to a method for manufacturing a prosthesis comprising a textile support and such a film.

Method of manufacturing an implantable film and prothesis comprising such a film

The present invention relates to a haemostatic patch comprising a porous layer based on oxidized cellulose and a neutralized film based on chitosan, said film comprising a free face and a face fixed on one of the faces of the porous layer, and to the method of preparing said patch comprising the following steps: &#x2014;a&#xb0;) preparing a porous layer based on oxidized cellulose, &#x2014;b&#xb0;) preparing a film based on chitosan starting from an acidic aqueous solution of chitosan, &#x2014;c&#xb0;) fixing the film obtained in b&#xb0;) on one face of the porous layer, &#x2014;d&#xb0;) neutralizing the film obtained in b&#xb0;), &#x2014;where step c&#xb0;) can be carried out before or after step d&#xb0;), characterized in that: the neutralizing step d&#xb0;) comprises treatment of said film with a neutralizing composition comprising at least ethanol and ammonium hydroxide (NHOH).

Haemostatic patch and method of preparation

The present invention relates to a process for washing a polysaccharide-based material which has been subjected to oxidation by at least one oxidizing agent, the said process comprising a first stage of washing with a first densified fluid which is inert with regard to the said oxidizing agent, characterized in that the first stage is followed by a second stage of washing with a washing composition comprising at least one second inert densified fluid and at least one alcohol. The said process according to the invention can additionally comprise a third stage of washing with a third inert densified fluid in order to remove the said alcohol deposited on the said polysaccharide-based material during the said second washing stage. Preferably, the said inert densified fluids are supercritical carbon dioxide.

Process for washing a polysaccharide-based material which has been subjected to an oxidation

Implants include a film layer containing cellulose secured to a surface of the porous layer that also contains cellulose, wherein the film layer is secured to the porous cellulose without the use of an adhesive.

Cellulose-containing medical device having a multi-layer structure produced without adhesive

The invention relates to a method for the controlled oxidation of oligo- and/or polysaccharides containing free &#x2014;CHOH primary hydroxyl groups, using an oxidizing agent. The invention is characterized in that the oxidation reaction is performed in a densified fluid which is inert in relation to the oxidizing agents employed. The invention is suitable for use, for example, in the food, paint, paper, textile, agricultural and pharmaceutical industries, in the medical, biomedical or paramedical fields, in the surgical field, in the cosmetic industry and as agents for the complexing or sequestering of metal ions, heavy metals and radioactive elements in the nuclear industry.

Growing community of inventors

Trevoux, France

Suzelei Montanari