National Research Council of Canada

University of Saskatchewan

Her Majesty the Queen in Right of Canada, As Represented by the National

Suzanne R Abrams

Adrian John Cutler

Lawrence V Gusta

Ken M Nelson

Patricia A Rose

Martin J Reaney

Naveen Diddi

Vishal Jheengut

Michele C Loewen

Jason Boyd

Bruce E Ewan

Leon Lai

Kenneth M Nelson

Bo Lei

James Nyangulu

Yuanzhu Gai

John J Balsevich

Patricia Rose

Adrian J Cutler

The present application relates to novel 3′-unsaturated abscisic acid (ABA) derivatives of Formula (I) as ABA antagonists. For example, the present application relates to methods of using compounds of Formula (I) for reducing adverse effects of an ABA response in plants such as lentil and promoting germination. (I) The present application also relates to methods of using 3′-phenyl abscisic acid (ABA) derivatives of Formula (II) as ABA antagonists, for example, for reducing adverse effects of an ABA response in plants such as lentil and promoting germination. (II)

3'-alkynyl abscisic acid derivatives as ABA antagonists

Methods are provided for synthesis of abscisic acid and 8' analogues thereof (including an enantiopure 8&#x2032;-acetylene analogue) including methods wherein the previously reported first step of oxidation of 2,6-dimethylphenol (VI) to 2,6-dimethylbenzoquinone, mono ketal (VII) is replaced by a novel two step process comprising (i) oxidation of 2,6-dimethylphenol (VI) using potassium peroxymonosulfate with a catalytic amount of iodobenzene to produce 2,6-dimethylbenzoquinone (XVI) and (ii) ketalization of 2,6-dimethylbenzoquinone (XVI) using ethylene glycol, trimethylorthoformate with a catalytic amount of p-toluenesulfonic acid to produce 2,6-dimethylbenzoquinone, mono ketal (VII).

Efficient scalable syntheses of abscisic acid, 8'-acetylene abscisic acid and 8&#x2032;-cyclopropyl abscisic acid

Bicyclic abscisic acid (ABA) analogs of Formula (I) and (II) and the process for their production are disclosed. The bicyclic ABA analogs include the structural elements and functional groups of the parent molecule that are required for activity, and have an aromatic ring fused to the ring replacing the vinyl methyl group of absicisie acid. Methods for using the bicyclic ABA analogs to inhibit cell growth and seed germination are also disclosed. 

Synthesis and biological activity of bicyclic ABA analogs

Inhibitors of a 9-cis epoxycarotenoid dioxygenase

Hyperabas: biologically active abscisic acid analogs with unsaturated

The present invention relates to a composition for enhancing synchrony of germination and emergence in plants and comprises an effective amount of a compound having the following general formula (I); ##STR1##

Use of compounds to enhance synchrony of germination and emergence in

Composition for enhancing germination and growth of plants which comprises an effective amount of at least one abscisic acid-related compound having the following formula (I): ##STR1##

Abscisic acid-related plant growth regulators - germination promoters

Growing community of inventors

Saskatoon, Canada

Suzanne R Abrams