Genzyme Corporation

Gtc Biotherapeutics, Inc.

Integrated Genetics, Inc.

Suzanne Groet

Katherine Gordon

Lothar Hennighausen

Robert Wydro

Jonathan Ostman

Heiner Westphal

A DNA sequence containing a gene encoding a protein, the gene being under the transcriptional control in the DNA sequence of a mammalian milk protein promoter which does not naturally control the transcription of the gene, such DNA sequence including DNA enabling secretion of the protein.

Transgenic animals secreting desired proteins into milk

Transgenic animals secreting proteins into milk

Method of binding nucleic acid to a nucleic acid-binding support comprising depositing the nucleic acid onto the support and then contacting the nucleic acid and the support with a liquid binding solution which is compatible with the support and which contains an organic solvent which is capable of binding the DNA to the support, for a period of time sufficient to effect the binding.

Binding nucleic acid to a support

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Sudbury, MA, United States of America

Suzanne Groet