Bausch-lomb Incorporated

Other

Suzanne F Groemminger

David J Heiler

Erning Xia

Kimberly Anne Millard

Joseph C Salamone

Joseph T Barr

Jenilee Kilbury

John Denick

Lisa C Simpson

David A Marsh

Nimai C De

Rick Panicucci

Shane Mao

The invention is directed to a method of cleaning and disinfecting a contact lens. The method includes instructing a consumer to disinfect their contact lens comprising the following steps: remove a contact from an eye and position the lens in a lens assembly that includes a cap member; add a disinfection solution to the lens case such that the lens is submerged in the solution upon closure of the lens case with the cap member. The disinfection solution will comprise 0.5 wt. % to 6 wt. % hydrogen peroxide or a chemical precursor of hydrogen peroxide, and a P-metal modulating compound. The presence of the P-metal modulating compound in the disinfection solution decreases the neutralization rate of the hydrogen peroxide. The disinfection system exhibits a pseudo first-order, half-life of hydrogen peroxide from 12 minutes to 30 minutes over an initial sixty minutes of neutralization following exposure of the disinfection solution to a catalyst comprising a P-metal. This reduction in rate of peroxide neutralization can provide a more effective solution for killing certain microorganisms and fungi.

Peroxide contact lens care solution

A contact lens disinfecting solution that comprises 0.5 wt. % to 6 wt. % hydrogen peroxide, or a chemical precursor of hydrogen peroxide, and a P-metal modulating compound. The presence of the P-metal modulating compound in the disinfecting hydrogen peroxide solution slows the rate at which the hydrogen peroxide is neutralized, particularly during the initial two hours, by a catalyst element that includes a P-metal. This reduction in rate of peroxide neutralization provides a more effective solution for killing certain microorganisms and fungi.

An in-eye method for cleaning contact lenses comprises use of a cleaner using water-containing beads. The water-containing beads are prepared such that the bead size is smaller than the punctual opening. They are easily flushed from the ocular environment by normal tear flow. The cleaner may also be used to clean contact lenses, with the cleaner applied directly to the lens and digitally rubbed to remove accumulated debris on the lens.

Method for in-eye cleaning of contact lens comprising polymeric beads

The present invention provides an optically clear, hydrophilic coating upon the surface of a silicone hydrogel lens by plasma treating the lens and subsequently heating the lens in an aqueous solution containing a surface-protective agent.

Surface treatment of silicone hydrogel contact lenses

A cleaning solution for contact lenses is described that includes a carbohydrate that is a mono- or disaccharide, its alcohols or partially hydrolyzed esters or mixtures thereof. Preferred carbohydrates are sorbitol, glucose, maltose, sucrose, dulcitol, dextran, dextrin, mannitol, maltitol, or mannose, preferably in an amount of 0.001 to 10% by weight of an aqueous solution for cleaning the contact lenses. A preferred composition for cleaning contact lenses comprises sorbitol in an amount of about 0.1 to 1% by weight in an aqueous solution. A method for cleaning contact lenses with said carbohydrate cleaning solution is described and may be combined, for simultaneously cleaning and disinfecting contact lenses, with a chemical, antimicrobial agent or thermal disinfecting regimen.

Carbohydrate composition and method for cleaning and disinfecting contact lenses

The present invention provides methods for treating contact lenses and compositions for the same. The present invention includes contacting a lens with an aqueous solution comprising a sulfobetaine compound represented by the formula: ##STR1## wherein: R.sub.1 is an alkyl group having from 8 to 30 carbon atoms, R.sub.2 and R.sub.3 are individually hydrogen or alkyl groups having from 1 to 4 carbon atoms, and R.sub.4 is an alkyl group having from 2 to 6 carbon atoms. In preferred embodiments of the invention, the subject compounds are used in combination with antimicrobial agents for providing simultaneous disinfection and cleaning of contact lenses.

Treatment of contact lenses with an aqueous solution including

Contact lenses are cleaned by contacting the lenses with a composition containing an effective amount of one or more cyclodextrins. The compositions can also be employed at elevated temperatures or may contain suitable antimicrobial agents in order to simultaneously clean and disinfect the lenses.

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Rochester, NY, United States of America

Suzanne F Groemminger