Ajinomoto Co., Ltd.

Susumu Shibahara

Yuki Miyazawa

Hidetsugu Nakazawa

Sachiko Oka

Yumi Goto

Koji Haga

Sachiko Yonemaru

Hiroyuki Sato

Takaaki Sato

Toru Ikeda

Nobuyoshi Kitamura

Makoto Takeuchi

Naoko Kanno

Hirokazu Morisawa

Takeo Ueda

Hiromi Suzuki

Kazunori Mawatari

Hideo Inoue

Sachiko Mukai

Tohru Nishihara

Kazuhiro Shimotori

Eiko Ohtsuka

Dispersion type feed additive compositions for ruminants, containing

Additive composition for ruminant feeds

Feed additive compositions for ruminants containing (A) at least one member selected from the group consisting of hydrogenated vegetable oil and hydrogenated animal oil each having a melting point of higher than 50&#xb0; C. and lower than 90&#xb0; C.; (B) not less than 0.05 wt % and not more than 6 wt % of lecithin; (C) not less than 30 wt % and less than 65 wt % of a biologically active substance; (D) not less than 0.01 wt % and less than 0.8 wt % of a natural vegetable oil; and not less than 0.1 wt % and less than 6 wt % of water exhibit high protection in the rumen and are also superior in dissolution in the lower gastrointestinal tract.

Feed additive composition for ruminants

Feed additive compositions for ruminants containing (A) at least one selected from hydrogenated vegetable oil and hydrogenated animal oil each having a melting point of higher than 50&#xb0; C. and lower than 90&#xb0; C., (B) lecithin, (C) a biologically active substance, (D) a natural vegetable oil, and water, wherein when a scattering profile is measured after maintaining at 40&#xb0; C. for 15 min, and then measured by further maintaining at 40&#xb0; C. for 30 min by a small-angle and wide-angle x-ray scattering method, a peak having the maximum peak intensity in a region where the scattering angle 2&#x3b8; is not more than 5&#xb0; has a ratio (t/s) of 0.9-1.1 wherein s is peak intensity when maintained at 40&#xb0; C. for 15 min and t is peak intensity when maintained at 40&#xb0; C. for 45 min, and a peak having the maximum peak intensity in a region where the scattering angle 2&#x3b8; is 17&#xb0;-23&#xb0; has a ratio (y/x) of 0.7-0.9 wherein x is peak intensity when maintained at 40&#xb0; C. for 15 min and y is peak intensity when maintained at 40&#xb0; C. for 45 min, have high protection in the rumen and are also superior in dissolution in the gastrointestinal tract.

A feed additive composition includes a protective agent, lecithin, an acidic or neutral amino acid, and water. A method of producing a feed additive composition includes preparing a molten mixture of a protective agent, lecithin, and an acidic or neutral amino acid, and immersing the molten mixture in water or an aqueous liquid to obtain a solidified mixture. Feed additives may be obtained by such method. The protective agent may include a hydrogenated vegetable oil or hydrogenated animal oil having a melting point of higher than 50&#xb0; C. and lower than 90&#xb0; C.

Feed additive composition for ruminants containing acidic or neutral amino acid, and method for production thereof

A feed additive composition includes a protective agent, lecithin in an amount of 0.05 to 6% by weight relative to a total weight of the composition, a basic amino acid in an amount of at least 40% by weight and less than 65% by weight relative to the total weight of the composition, and water. A method of producing a feed additive composition includes preparing a molten mixture of at least one protective agent, lecithin and at least one basic amino acid, and solidifying the molten mixture by immersing the molten mixture in water or an aqueous liquid. The protective agent includes hydrogenated vegetable oils and/or hydrogenated animal oils having melting points of greater than 50&#xb0; C. and less than 90&#xb0; C.

Feed additive composition for ruminants and method of producing the same

A food additive composition for ruminants of the dispersion type and a method of continuously producing the same. This food additive composition for ruminants, which contains 40% by weight or more but less than 65% by weight of a basic amino acid and has rumen bypass properties, is formulated into granules in an arbitrary shape which are scarcely classified when added to a silage or another feed. Thus, attempts have been made to develop a method of producing granules by which the milk yield of a lactation cow can be increased. Namely, it is intended to provide a food additive composition for ruminants which contains at least one protecting agent selected from among a hardened vegetable oil and a hardened animal oil having a melting point higher than 50&#xb0; C. but lower than 90&#xb0; C., 0.05 to 6% by weight of lecithin, water and 40% by weight or more but less than 65% by weight of a basic amino acid. It is also intended to provide a method of producing a food additive composition for ruminants characterized by comprising solidifying a molten mixture, which comprises at least one protecting agent selected from among a hardened vegetable oil and a hardened animal oil having a melting point higher than 50&#xb0; C. but lower than 90&#xb0; C., lecithin and a basic amino acid, by dipping in water.

Effective preventive method for infectious diseases, an enhancing method of an infectious disease-preventive action of cystine and composition, food and feed effective for infectious diseases are provided. A method of preventing infectious diseases wherein cystine and the like and theanine are administered in combination, a method of enhancing an infectious disease-preventive action of cystine and the like, which contains administering cystine and the like and theanine in combination, a pharmaceutical composition, food and feed wherein cystine and the like and theanine are combined.

Method of preventing infectious diseases

A composition comprising modified milk powder, and glutamine and/or a peptide containing glutamine.

Modified milk powder composition

The invention relates to biologically active substances coated with a coating composition containing at least one substance selected from the group consisting of hardened vegetable fats and oils, hardened animal fats and oils, fatty acid esters and phospholipids and an enzyme and/or enzyme activator where the outermost surface portion of the coating layer contains substantially no enzyme and/or enzyme activator. The invention materials exhibit excellent protection in the rumen of ruminant animals and allow for the dissolution in the post-abomasum lower digestive organs of the ruminant.

Granular feed additives for ruminants containing lipase, bile powder and

A granular additive composition for ruminant feed which stably protects a biologically active substance in the rumen of the ruminant and allows it to be effectively digested and absorbed in the digestive organs after the abomasum.

There is disclosed a compound having a double chain which is composed of an RNA (+chain) and a complementary DNA (-chain), wherein a portion of the DNA (-chain) has been replaced by an RNA or a derivative thereof, and wherein, when the compound is subjected to the action of an enzyme having a ribonuclease H activity, it is possible to preferentially cleave the RNA (+chain) in a position corresponding to the unsubstituted portion of the DNA (-chain). The compound can thus be used for the preferential cleavage of a phosphodiester bond in a specific position of RNA. Accordingly, the invention provides a useful means for preparing, for instance, a deletion mutant. There is also disclosed a mixed oligomer which comprises an oligomer of RNA or a derivative thereof and a DNA oligomer, wherein the RNA oligomer or a derivative thereof is conjugated to the DNA oligomer via a phosphate diester linkage between the 5'-hydroxyl group and the 3'-hydroxyl group in the ribose or deoxyribose moiety. There is further disclosed a nucleoside derivative of a given general formula for use as a starting material.

Growing community of inventors

Kawasaki, Japan

Susumu Shibahara