Kyowa Hakko Kogyo Co., Ltd.

Mitsubishi Heavy Industries Limited

Kyowa Hakko Kirin Co., Limited

Other

Kyoto University

Juridical Foundation, Japanese Foundation for Cancer Research

Toa Steel Co., Ltd.

Susumu Sekine

Katsutoshi Sasaki

Seiga Itoh

Satoshi Nakagawa

Yutaka Kano

Moriyuki Sato

Tatsunari Nishi

Tomoyuki Yamazaki

Toshiyuki Wada

Akiko Saito

Ayumi Natsume

Hiroto Akitaya

Kenji Shibata

Yuki Kobayashi

Akiko Furuya

Mitsuo Satoh

Kazuya Yamano

Toshio Ota

Sumio Sugano

Miho Takebayashi

Nobuo Hanai

Yusuke Nakamura

Minoru Fukuda

Tamio Mizukami

Mamoru Hasegawa

Tetsuro Kuga

Tomoyuki Kojima

Daiki Fujimura

Akihiro Iida

Hyota Abe

Norihiko Shiraishi

Kazumi Miura

Yoji Yamada

Youichi Nabeshima

Hisashi Narimatsu

Hiroyuki Mio

Akira Togayachi

Etsuyo Watanabe

Makoto Kuroo

Kunikatsu Shirahata

Kazuo Yamaguchi

Tadatsugu Taniguchi

Haruo Sugano

Tadashi Ota

Tetsuya Hirano

Shingo Yamasue

Katsumi Ito

Mitsuaki Yoshida

Toyoaki Eguchi

Hiroshi Kawauchi

Noriyoshi Ohwada

Kazuki Kitagawa

Takayuki Ikarashi

Hirofumi Ohara

Hiromitsu Mori

Taiichi Mure

A diagnosis apparatus for a valve system including a control valve, a servo valve for driving the control valve, and at least one servo module for providing a control signal based on an opening degree command value for the control valve to the servo valve is provided with: at least one opening degree detection part configured to detect an actual opening degree of the control valve; and a diagnosis part configured to acquire, from the opening degree detection part, a detected value of the actual opening degree of the control valve while a diagnostic opening degree command value is input to the at least one servo module, and diagnose an abnormality of the valve system on the basis of the detected value. The diagnostic opening degree command value changes in multiple steps between a maximum opening degree and a minimum opening degree through one or more intermediate opening degrees.

Diagnosis apparatus, diagnosis method, and diagnosis program for valve system

A member attachment support system is for supporting work of attaching a plurality of members to a device. The member attachment support system includes: an identification information storage unit provided for each of the plurality of members and configured to store identification information associated with an attachment position of each of the plurality of members; a terminal device configured to acquire the identification information from the identification information storage unit; and a display device configured to display a support image that indicates the attachment position corresponding to the identification information acquired by the terminal device.

Member attachment support system and member attachment support method

Display screen with graphical user interface for fuel valve diagnosis

A steam turbine plant and an operating method thereof, and a combined cycle plant and an operating method thereof, include: a turbine; steam supply lines that supply main steam to the turbine; a steam control valve and an intercept valve provided to the steam supply lines; and a first auxiliary steam supply line that supplies auxiliary steam to the turbine via the steam supply lines which are located farther downstream than the steam control valve and the intercept valve.

Steam turbine plant and operation method, combined cycle plant and operation method

A heat insulating material assembly is provided with: a heat insulating material covering an outer surface of a casing of a gas turbine; and a guard part disposed so as to protrude from the outer surface of the casing and face an end surface of the heat insulating material. The heat insulating material is disposed outside an arrangement area of a plurality of openings for air intake from an external space into the casing and on an opposite side to the arrangement area across the guard part.

Heat insulating material assembly and gas turbine

Display screen with transitional graphical user interface

A steam turbine plant is provided with: a boiler; a fuel valve; a low-temperature steam generation source; a steam turbine; a main steam line that guides steam generated in the boiler to the steam turbine; a main steam adjustment valve that is provided to the main steam line; a low-temperature steam line that guides low-temperature steam from the low-temperature generation source to a position closer to the steam turbine-side than the main steam adjustment valve in the main steam line; a low-temperature steam valve provided to the low-temperature steam line; and a control device. During a stopping process of the steam turbine plant, the control device sends a command to close the fuel valve, and then sends a command to open the low-temperature steam valve.

Steam turbine plant and cooling method for same

The present invention provides a novel polypeptide having a &#x3b2;1,3-N-acetylglucosaminyltransferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a recombinant vector into which the DNA is inserted; a transformant comprising the recombinant vector; a method for producing a sugar chain or complex carbohydrate, using the polypeptide; a method for producing a sugar chain or complex carbohydrate, using the transformant; an antibody which recognizes the polypeptide; a method for screening a substance which changes the expression of the gene which encodes the polypeptide; and a method for screening a substance which changes the activity of the polypeptide.

Methods for synthesizing sugar chains using &#x3b2;1,3-N-acetylglucosaminyltransferase

Using the proteins of the present invention, DNAs encoding the proteins, and antibodies recognizing the proteins, detection methods for diseases relating to the novel insulin-like growth factor binding proteins of the present invention, as well as diagnostic agents, preventive agents, and therapeutic agents for diseases relating to the proteins of the present invention can be provided.

Antibodies to insulin-like growth factor binding protein and uses thereof

The present invention relates to a polypeptide having an activity of suppressing aging; DNA encoding the polypeptide; a method for improving livestock, using the DNA; a recombinant DNA prepared by inserting the DNA into a vector; a transformant harboring the recombinant; a method for preparing the polypeptide of the present invention, using the transformant; an antibody which recognizes the polypeptide; a ligand for the polypeptide of the present invention; a compound inhibiting specific binding between the polypeptide and ligand of the present invention; a compound enhancing the expression of an aging-suppressing gene encoding the aging-suppressing polypeptide of the present invention; an oligonucleotide comprising a sequence of 10 to 50 nucleotides in the nucleotide sequence of the DNA; and a therapeutic agent for a syndrome resembling premature aging, a therapeutic agent for adult diseases or an aging-suppressing agent, using the same.

Polypeptide, novel DNA and novel antibody

The present invention provides a novel polypeptide having a &#x3b2;1,3-N-acetylglucosaminyltransferase activity, an agent for synthesizing a sugar chain comprising the polypeptide, a process for producing a sugar chain or a complex carbohydrate using the agent for synthesizing a sugar chain, DNA encoding the polypeptide, a process for producing the polypeptide, an antibody against the polypeptide, and a diagnosis method and a medicament for treatment for inflammation, cancer or tumor metastasis using the DNA or the antibody. The present invention is useful for synthesis of a useful sugar chain and diagnosis and treatment for inflammatory diseases, cancer or tumor metastasis.

Transformed cell harboring DNA or RNA encoding sugar chain synthesizing agent having &#x3b2;1,3-N-acetylglucosaminyltransferase activity

Insulin-like growth factor binding protein

The present invention provides pharmaceutical preparations for anti-inflammation, anti-infection, inhibition of cancer metastasis etc., foods such as dairy products etc., and a method for improving proteins, as well as a method for diagnosis of inflammatory diseases and cancer malignancy. According to the present invention, there can be provided a polypeptide having poly-N-acetyllactosamine sugar chains synthesis-related activity, a process for producing the polypeptide, DNA coding for the polypeptide, a process for producing the DNA, a recombinant vector having the DNA integrated therein, a transformant carrying the recombinant vector, an antibody recognizing the polypeptide, a process for producing poly-N-acetyllactosamine sugar chains by use of the DNA or the polypeptide, diagnosis and treatment of diseases such as inflammations, cancers etc. by use of the DNA, the polypeptide or the antibody, determination and immunostaining of the polypeptide of the present invention by use of the antibody, a method for screening a compound varying the expression of a gene coding for the polypeptide, and a method for screening a substance varying the activity of the polypeptide.

Polypeptides

Growing community of inventors

Yokohama, Japan

Susumu Sekine