Taisho Pharmaceutical Co., Ltd.

The Green Cross Corporation

Daikin Industries, Ltd.

Kyoto University

Susumu Otomo

Kazumasa Yokoyama

Tadakazu Suyama

Yutaka Mizushima

Hiroyuki Okamoto

Hironaka Aihara

Katsuo Hatayama

Tohru Tanami

Takehiro Amano

Yutaka Kawashima

Kazuhiro Shimokawa

Toru Yoshizawa

Shigeru Okuyama

Yorisato Hisanaga

Tsutomu Kagiya

Seiichi Nishimoto

Mitsuyuki Abe

Yuta Shibamoto

Seiichi Takano

Use of 2-nitroxyethyl (+)apovincaminate

A 2-nitroimidazole derivative of the formula: ##STR1## wherein R.sub.f is a group of the following formula (II) or (III):

Fluorine-containing 2-nitroimidazole derivatives

A fat emulsion containing a prostaglandin E.sub.1 alkyl ester represented by the general formula ##STR1## wherein R denotes an alkyl group having 1 to 30 carbon atoms. The fat emulsion can be administered intravenously, has a long half-life of its effective ingredient, prostaglandin E.sub.1 alkyl ester, in the living body as well as a focus selectivity.

Fat emulsion containing prostaglandin

A fat emulsion for injection containing prostaglandin E.sub.1 which has a vasodilative action as well as a hypotensive action and a method for the production of such an emulsion. The present emulsion is effective in treating chronic arteriostenosis diseases.

Fat emulsion containing prostaglandin E.sub.1 and method for production

A novel thiazolidine derivative having the following general formula ##STR1## wherein R.sup.1 and R.sup.2 are each lower alkyl having 1 to 3 carbon atoms, or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are attached form a heterocyclic ring selected from the group consisting of morpholino, piperazino, piperidino and pyrrolidino, or said heterocyclic ring substituted with 1 or 2 methyl groups, and the pharmaceutically acceptable salts thereof are useful immunomodulators.

4-Carboxy-2-acetamido thiazolidine derivatives

Growing community of inventors

Kounosu, Japan

Susumu Otomo