Teijin Limited

Teijin Pharma Limited

Takeda Gmbh

Susumu Maruo

Osafumi Hidaka

Satoshi Murakami

Takanori Miyoshi

Takeyuki Kawaguchi

Hiroyoshi Minematsu

Hiroaki Kuwahara

Ryo Furukawa

Atsuhiro Nagano

Kentaro Fujinaga

Tsutomu Mochizuki

Michio Iwai

Kiyomi Ishida

Michiharu Kageyama

Kenji Sunagawa

Hideaki Nakamura

Yuko Nonaka

The present invention is intended to provide a nose drop having high absorption of peptide hormone oxytocin or an acid addition salt thereof, or a derivative thereof through nasal mucosa and little safety concern. The present invention is a pharmaceutical composition for administration to nasal mucosa containing oxytocin or an acid addition salt thereof, or a derivative thereof and a carboxyvinyl polymer, characterized by having an osmotic pressure ratio less than 1.

Pharmaceutical composition for administration to nasal mucosa

Disclosed is a controlled release nucleated tablet which is composed of an inner nucleus and an outer layer that covers the inner nucleus and is capable of maintaining the level of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid in the blood to a certain value or higher for a long period of time. The controlled release nucleated tablet is characterized in that the inner nucleus contains 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and the outer layer contains 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and a gel-forming water-soluble polymer that is in an amount of 16 (w/w) % or more relative to the weight of the outer layer.

Controlled release coat-core tablet

The present invention relates to a sterile aqueous suspension containing ciclesonide, a microgel and a water soluble ionic polymer. The present invention provides a sterile aqueous suspension in which ciclesonide is dispersed homogeneously over a long period of time.

Ciclesonide containing sterile aqueous suspension

An ointment patch includes a support, an ointment, and optionally, a separator. In this ointment patch, the ointment is coated on one surface of the support in an amount of 0.1 mg to 200 mg per 1 cmof the support, and the support has a thickness of 1 &#x3bc;m to 2000 &#x3bc;m and 50% modulus of 5 g/cm to 600 g/cm.

Member for application of ointment and ointment patch employing the same

A patch comprising an adhesive layer formed on one surface of a flexible support, wherein said adhesive layer containing a drug, an absorption enhancer and an adhesive comprising;

Patches containing buprenorphine hydrochloride

The gel adhesive of the present invention contains an elastomer component (A), a self-adhesive polymer component (B) compatible with the elastomer component (A), and a liquid component (C) compatible with the elastomer component (A) and the self-adhesive polymer (B), the liquid component (C) being held in a mixture of the elastomer component (A) and the self-adhesive polymer (B) without exuding, to form as a whole, a gel, and is useful for forming a self-adhesive layer of an adhesive material or a pharmaceutical-containing self-adhesive layer of an adhering pharmaceutical preparation, which layer is capable of being firmly adhered to a surface to be adhered, and particularly a body skin surface, and of being easily removed therefrom without leaving a portion of the layer on the adhered surface.

Gel-form pressure-sensitive adhesive, and adhesive material and adhesive medicinal preparation both containing the same

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Tokyo, Japan

Susumu Maruo