Forschungszentrum Juelich Gmbh

Heinrich-heine-universitaet

Forschungszentrum Julich Gmbh

Priavoid Gmbh

Heinrich-heine-universität

Susanne Aileen Funke

Dieter Willbold

Dirk Bartnik

Luitgard Nagel-Steger

Oleksander Brener

Carsten Korth

Hans-Ulrich Demuth

Martin Kleinschmidt

Antonia Nicole Klein

Janine Kutzsche

Oliver Bannach

Steffen Huebinger

Yeliz Cinar

Hans-Henning Ludwig

Kateryna Kravchenko

Andreas Mueller-Schiffmann

Andreas Müller-Schiffmann

Stephan Rudolph

Heiner Schaal

Eva Birkmann

Verian Bader

Marek Widera

Lei Wang-Dietrich

The invention concerns a method for detecting indicators for determining diseases (disease indicators), in which aggregates of misfolded proteins play a role, and a method for selective quantitation and/or characterization of these disease indicators.

Method for detecting indicators for determining diseases

The present invention relates to novel D-enantiomeric A-beta-oligomer-binding peptides, homologs, fragments, parts and polymers thereof and use thereof.

D-enantiomeric peptides derived from D3 and use thereof

Peptides specifically binding amyloid beta and to methods of treating and diagnosing Alzheimer's dementia using such peptides are provided.

Specific amyloid beta binding peptides and the use of same for treating and diagnosing alzheimer's dementia

An agent for preventing and/or treating HIV and other viral infections. The agent in particular comprises at least one peptide, including an amino acid sequence, which is suitable for preventing fibrils associated with Alzheimer's disease, and/or homologs, fractions and parts thereof, so as to treat and/or prevent HIV and/or other viral infections.

Agents for preventing and treating HIV and other viral infections

Peptides that bind to amino-terminal truncated pEA&#x3b2;3-42, the free glutamic acid residue of which lies in position 3 or 11 in the form of cyclized pyroglutamate. Four oligopeptides were identified using mirror image phage display technology.

Peptides that bind to amino-truncated amyloid-beta-peptide and use of said peptides

The present invention relates to novel tau protein aggregate-binding peptides, homologs, fragments, parts and polymers thereof and to the use thereof.

Peptides for the treatment and early diagnosis of Alzheimer's disease and other tauopathies

The invention relates to novel multivalent polymeric amyloid-beta-binding substances composed of several interconnected substances which per se already have amyloid-beta-binding properties, and to the use of these substances, referred to hereinbelow as 'polymers', in particular in medicine.

Polymers containing multivalent amyloid-beta-binding D-peptides and their use

A composition includes D-peptides or antibodies to at least one of to prevent a disease and to treat the disease, wherein the D-peptides interact with an amyloid peptide and the antibodies bind to both the D-peptide and the amyloid peptide.

Composition for producing anti-amyloid beta peptide antibodies with D-peptides

Growing community of inventors

Sonnefeld, Germany

Susanne Aileen Funke