Covagen Ag

Susann König-Friedrich

Dragan Grabulovski

Julian Bertschinger

Patricia Henne

Ulrike Von Der Bey

Isabella Attinger-Toller

Fabian Buller

Ulrich Wüllner

Irene Zbinden

The present invention relates to a polypeptide binding to human serum albumin and comprising or consisting of an amino acid sequence selected from the group consisting of: (a) GVTLFVALYDY(X)(X)(X)(X)(X)(X)D(X)SFHKGEKFQIL(X)(X)(X)(X)(X)G(X)(X)W(X)(X)RSLTTG(X)(X)G(X)IPSNYVAPVDSIQ (SEQ ID NO: 1), wherein (X) is A, V, I, L, M, G, P, S, T, N, Q, C, R, H, K, D or E; (X) is R, H, K, A, V, I, L, M, G, P, S, T, N, Q or C; (X) is R, H, K, S, T, N, Q, C, F, Y, W, A, V, I, L, M, G or P; (X) is S, T, N, Q, C, A, V, I, L, M, G, P, R, H, K, F, Y, W, D or E; (X) is S, T, N, Q, C, D, E, F, Y, W, A, V, I, L, M, G, P, R, H or K; (X) is F, Y, W, A, V, I, L, M, G, P, R, H, K, S, T, N, Q or C; (X) is A, V, I, L, M, G, P, R, H or K; (X) is S, T, N, Q, C, D or E; (X) is S, T, N, Q, C, D, E, A, V, I, L, M, G, P, F, Y or W; (X) is A, V, I, L, M, G or P; (X) is F, Y, W, R, H or K; (X) is S, T, N, Q, C, F, Y or W; (X) is F, Y, W, R, H, K, S, T, N, Q, C, D, E, A, V, I, L, M, G or P; (X) is F, Y, W, A, V, I, L, M, G or P; (X) is D, E, A, V, I, L, M, G or P; (X) is A, V, I, L, M, G or P; (X) is D, E, A, V, I, L, M, G, P, R, H or K; (X) is S, T, N, Q, C, A, V, I, L, M, G or P; (X) is F, Y, W S, T, N, Q or C; and (b) an amino acid sequence which is at least 90% identical to the amino acid sequence of (a), wherein the identity determination excludes amino acid positions (X) to (X).

Human serum albumin binding compounds and fusion proteins thereof

The present invention relates to a polypeptide binding to human serum albumin and comprising or consisting of an amino acid sequence selected from the group consisting of: (a) GVTLFVALYDY(X)(X)(X)(X)(X) (X)D(X)SFHKGEKFQIL(X)(X)(X)(X)(X)G(X)(X)W(X)(X)RSLTTG(X)(X)G(X)IPSNYVAPVDSIQ (SEQ ID NO: 1), wherein (X) is A, V, I, L, M, G, P, S, T, N, Q, C, R, H, K, D or E; (X) is R, H, K, A, V, I, L, M, G, P, S, T, N, Q or C; (X) is R, H, K, S, T, N, Q, C, F, Y, W, A, V, I, L, M, G or P; (X) is S, T, N, Q, C, A, V, I, L, M, G, P, R, H, K, F, Y, W, D or E; (X) is S, T, N, Q, C, D, E, F, Y, W, A, V, I, L, M, G, P, R, H or K; (X) is F, Y, W, A, V, I, L, M, G, P, R, H, K, S, T, N, Q or C; (X) is A, V, I, L, M, G, P, R, H or K; (X) is S, T, N, Q, C, D or E; (X) is S, T, N, Q, C, D, E, A, V, I, L, M, G, P, F, Y or W; (X) is A, V, I, L, M, G or P; (X) is F, Y, W, R, H or K; (X) is S, T, N, Q, C, F, Y or W; (X) is F, Y, W, R, H, K, S, T, N, Q, C, D, E, A, V, I, L, M, G or P; (X) is F, Y, W, A, V, I, L, M, G or P; (X) is D, E, A, V, I, L, M, G or P; (X) is A, V, I, L, M, G or P; (X) is D, E, A, V, I, L, M, G, P, R, H or K; (X) is S, T, N, Q, C, A, V, I, L, M, G or P; (X) is F, Y, W, S, T, N, Q or C; and (b) an amino acid sequence which is at least 90% identical to the amino acid sequence of (a), wherein the identity determination excludes amino acid positions (X) to (X).

Growing community of inventors

Gottmadingen, Germany

Susann König-Friedrich