Laboratorios Del Dr. Esteve S.a.

Laboratories Del Dr. Esteve S.a.

Susana Yenes Mínguez

Helmut Heinrich Buschmann

Antoni Torrens Jover

Alberto Dordal Zueras

Josep Mas Prió

Luz Romero Alonso

Helmut H Buschmann

The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.

5-HT7 receptor antagonists

The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some 2,2a,4,5-tetrahydro-1H-3-aza-acenaphthylen substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.

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Barcelona, Spain

Susana Yenes Mínguez