Fundacíon Tecnalia Research & Innovation

Susana Caballero Román

José Ramón Ochoa Gómez

María Del Mar Díaz De Guereñu Zabarte

Soraya Prieto Fernández

Inés Rincón Arroyo

Tomás Roncal Martínez

The present invention provides a modified strain of the bacteriumobtainable by a method that comprises a step of fusion of two protoplasts from twoparental strains which, compared to the wild type strain offrom which they derive, show: (a) an increased ability to produce acetoin and/or 2,3-butanediol (2,3-BDO), and (b) a decreased ability to produce lactic acid, when cultured under aerobic conditions, and wherein the modified strain ofhas an increased ability to produce 2,3-BDO of at least 20 times the amount produced by the wild type strain, an increased ability to produce acetoin of at least 20 times the amount produced by the wild type strain and a decreased ability to produce lactic acid of at least 10 times the amount produced by the wild type strain, when cultured under aerobic conditions. Also provided are methods to produce acetoin and 2,3-BDO.

Growing community of inventors

Donostia-San Sebastián, Spain

Susana Caballero Román