University of Massachusetts

Centers for Disease Control and Prevention

Susan Sloan

Gregory Babcock

William D Thomas, Jr

Donna Ambrosino

Robert Barry Mandell

Charles E Rupprecht

William D Thomas

Gregory J Babcock

Teresa J Broering

Robert Mandell

Isolated human monoclonal antibodies which bind to hepatitis C virus (HCV), and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced in a transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals, and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.

Human antibodies against hepatitis C virus (HCV) and uses thereof

Human monoclonal antibodies that specifically bind to rabies virus, antigen binding portions thereof, and methods of making and using such antibodies and antigen binding portions thereof for treating rabies virus in a subject, are provided herein.

Human antibodies against rabies and uses thereof

Growing community of inventors

Watertown, MA, United States of America

Susan Sloan