Glaxo Group Limited

Smithkline Beecham Corporation

Susan Roomans

Gerard Martin Paul Giblin

Ann Louise Walker

Andrew McMurtrie Mason

Neil Derek Miller

Alessandra Gaiba

Martin Edward Swarbrick

Miles Stuart Congreve

Christopher Norbert Johnson

David Kenneth Dean

Steven James Stanway

Daryl Simon Walter

Mark Patrick Healy

Laura J Chambers

Stephen Vernon Frye

Haydn Terence Jones

Stephen Edward Shanahan

Paul John Beswick

A compound of formula (I) or a pharmaceutically acceptable derivative thereof, wherein, R, R, R, R, R, m, n and X are as defined in the specification; a process for preparing such compounds; a pharmaceutical composition comprising such compounds; and the use of such compounds in medicine.

[object Object]

A compound of formula (I) or salts thereof, wherein R, R, R, R, n and X are as defined in the specification; a process for preparing such compounds, a pharmaceutical composition comprising such compounds; and the use of such compounds in medicine.

Compounds

Naphthalene derivatives

Compounds of formula (I) and pharmaceutically acceptable derivatives thereof bind with high affinity to the EP4 receptor and are of use in the treatment or prevention of conditions such as a pain, inflammatory, immunological, bone, neurodegenerative or renal disorder.

Benzo (f) insoindol derivatives and their use as ep4 receptor ligands

Compounds of formula (I)and pharmaceutically acceptable derivatives thereof bind with high affinity to the EP4 receptor and are of use in the treatment or prevention of conditions such as a pain, inflammatory, immunological, bone, neurodegenerative or renal disorder.

Naphathalene derivatives which bind to the EP4 receptor

Growing community of inventors

Harlow, United Kingdom

Susan Roomans