Bausch-lomb Incorporated

Other

Susan P Spooner

David J Heiler

Stephen E Maier

Erning Xia

David J McCanna

The invention is directed to compositions and methods used as in-the-eye and/or out-of-eye inhibitors of proteinaceous deposits on hydrophilic contact lenses. Compositions of the present invention comprise moderately charged polyquaternium polymers that selectively bind to hydrophilic contact lenses to block the binding of proteinaceous materials. Compositions of the present invention may be used in multipurpose cleaning solutions for contact lenses and can eliminate the need for special enzyme cleaners and the like for removing proteinaceous materials.

Composition and method for inhibiting of protein on contact lens

The present invention is directed to an ophthalmically safe disinfecting solution for contact lenses comprising the combination of a polymeric biguanide and a polyquaternium polymer of a substituted or unsubstituted vinylimidazole or its vinylimidazoliuum salt, which copolymer has a weight average molecular weight of 5,000 to 5,000,000. The invention is also directed to an improved method of disinfecting a contact lens.

Compositions comprising polyquaterniums in combination with polymeric

Method for inhibiting the deposition of protein on contact lens

The present invention provides methods for treating contact lenses and compositions for the same. The present invention includes contacting a lens with an aqueous solution comprising a pyrrolidone compound represented by the formula: ##STR1## wherein: R is a hydrogen or an alkyl group having from 1 to 6 carbon atoms. In preferred embodiments of the invention, the subject compounds are used in combination with antimicrobial agents for providing simultaneous disinfection and cleaning of contact lenses.

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Rochester, NY, United States of America

Susan P Spooner